Open Innovation as the Catalyst in the Personalized Medicine to Personalized Digital Medicine Transition

Abstract

Personalized medicine (PM) bridges several disciplines for understanding and addressing prevalent, complex, or rare situations in human health (e.g., complex phenotyping, risk stratification, etc.); therefore, digital and technological solutions have been integrated in the field to boost innovation and new knowledge generation. The open innovation (OI) paradigm proposes a method by which to respectfully manage disruptive change in biomedical organizations, as experienced by many organizations during digital transformation and the COVID-19 pandemic. In this article, we focus on how this paradigm has catalyzed the transition from PM to personalized digital medicine in a large-volume research hospital. Methods, challenges, and results are discussed. This case study is an endeavor to confirm that OI strategies could help manage urgent needs from the healthcare environment, while achieving sustainability-oriented, accountable innovation.

Challenges and solutions to system-wide use of precision oncology as the standard of care paradigm

“…This highlights the need for potential strategic collaborations among academic institutions, industries, and healthcare providers in catalysing innovation and providing pragmatic and scalable solutions. Creating and nurturing a culture of continuous learning and innovation within these institutions is essential, but difficult to achieve despite public and private grant opportunities often spotlighted as key innovation drivers (Cesario et al, 2022 ).…”