Ophthalmologic Applications

Sheardown, Heather; Hicks, Emily Anne; Tayab, Aftab; Muirhead, Ben B

doi:10.1016/b978-0-12-816137-1.00072-6

Cited by 3 publications

(1 citation statement)

References 76 publications

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“…Contact lenses made from vinyl polymers with high surface wettability and lubricity provide wearers with a more comfortable and enjoyable wearing experience. [ 29 ]…”

Section: Materials Properties Of Vinyl Polymersmentioning

confidence: 99%

Vinyl Polymers as Key Materials in Contact Lens Design: A Review of Progress and Future Directions

Shaker,

Al‐Amiery,

Isahak

et al. 2024

Starch Stärke

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Vinyl polymers, crucial in contemporary contact lens design, present unique attributes with promising implications for vision correction. This comprehensive review navigates the trajectory and future trajectories of vinyl polymer‐based contact lenses. The introduction underscores the vital role of contact lenses in vision correction and positions vinyl polymers as ideal materials due to their exceptional properties. Delving into material specifics—high oxygen permeability, optical clarity, surface wettability, and mechanical strength—the analysis emphasizes their influence on corneal health, comfort, and durability. The versatility of manufacturing techniques, encompassing spin casting, molding processes, polymerization, and surface modification, underscores their feasibility in crafting high‐quality lenses. Examining clinical applications, encompassing daily disposables, extended wear, silicone hydrogel, and specialty lenses, alongside biocompatibility assessments and user feedback, provides a nuanced understanding of vinyl polymer‐based lens effectiveness. The article candidly addresses challenges—dehydration, deposits, mechanical stability, and durability—alongside regulatory considerations. Future prospects involve novel formulations, smart materials, bioinspired designs, and noninvasive technologies to amplify comfort and performance. In conclusion, this review distills progress, acknowledges challenges, and charts a sanguine course for vinyl polymer materials in advancing contact lens design, envisioning a future marked by enhanced vision correction technologies.

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“…Contact lenses made from vinyl polymers with high surface wettability and lubricity provide wearers with a more comfortable and enjoyable wearing experience. [ 29 ]…”

Section: Materials Properties Of Vinyl Polymersmentioning

confidence: 99%

Vinyl Polymers as Key Materials in Contact Lens Design: A Review of Progress and Future Directions

Shaker,

Al‐Amiery,

Isahak

et al. 2024

Starch Stärke

View full text Add to dashboard Cite

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Advancements in the chemistry of contact Lenses: Innovations and applications

Abdulamier,

Shaker,

Al-Amiery

2024

Results in Chemistry

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Application of Silicone in Ophthalmology: A Review

Mladenovic,

Zivic,

Petrovic

et al. 2024

Materials

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This paper reviews the latest trends and applications of silicone in ophthalmology, especially related to intraocular lenses (IOLs). Silicone, or siloxane elastomer, as a synthetic polymer, has excellent biocompatibility, high chemical inertness, and hydrophobicity, enabling wide biomedical applications. The physicochemical properties of silicone are reviewed. A review of methods for mechanical and in vivo characterization of IOLs is presented as a prospective research area, since there are only a few available technologies, even though these properties are vital to ensure medical safety and suitability for clinical use, especially if long-term function is considered. IOLs represent permanent implants to replace the natural lens or for correcting vision, with the first commercial foldable lens made of silicone. Biological aspects of posterior capsular opacification have been reviewed, including the effects of the implanted silicone IOL. However, certain issues with silicone IOLs are still challenging and some conditions can prevent its application in all patients. The latest trends in nanotechnology solutions have been reviewed. Surface modifications of silicone IOLs are an efficient approach to further improve biocompatibility or to enable drug-eluting function. Different surface modifications, including coatings, can provide long-term treatments for various medical conditions or medical diagnoses through the incorporation of sensory functions. It is essential that IOL optical characteristics remain unchanged in case of drug incorporation and the application of nanoparticles can enable it. However, clinical trials related to these advanced technologies are still missing, thus preventing their clinical applications at this moment.

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Ophthalmologic Applications

Cited by 3 publications

References 76 publications

Vinyl Polymers as Key Materials in Contact Lens Design: A Review of Progress and Future Directions

Vinyl Polymers as Key Materials in Contact Lens Design: A Review of Progress and Future Directions

Advancements in the chemistry of contact Lenses: Innovations and applications

Application of Silicone in Ophthalmology: A Review

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