Opioid-induced Hyperalgesia: An Entity not so Common, but exists

Abstract

Reported are cases of opioid-induced hyperalgesia (OIH) which is a rare entity to be seen by pain physicians. It occurs in patients treated with long term opioids which is perceived in the form of hyperalgesia or allodynia. It is a clinical challenge to treat such cancer patients and opioid addict individuals. The understand ing of OIH mechanism, manifesta tions as well as treatment is important for any pain physician.