2019
DOI: 10.1136/bmjopen-2019-030062
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Opportunities for antibiotic optimisation and outcome improvement in patients with negative blood cultures: study protocol for a cluster-randomised crossover trial, the NO-BACT study

Abstract: IntroductionPatients with negative blood cultures (BCx) represent 85%–90% of all patients with BCx taken during hospital admission. This population usually includes a heterogeneous group of patients admitted with infectious diseases or febrile syndromes that require a blood culture. There is very little evidence of the clinical characteristics and antibiotic treatment given to these patients.Methods and analysisIn a preliminary exploratory prospective cohort study of patients with BCx taken, the clinical/thera… Show more

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