2016
DOI: 10.3389/fneur.2016.00021
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Opportunities for Guided Multichannel Non-invasive Transcranial Current Stimulation in Poststroke Rehabilitation

Abstract: Stroke is a leading cause of serious long-term disability worldwide. Functional outcome depends on stroke location, severity, and early intervention. Conventional rehabilitation strategies have limited effectiveness, and new treatments still fail to keep pace, in part due to a lack of understanding of the different stages in brain recovery and the vast heterogeneity in the poststroke population. Innovative methodologies for restorative neurorehabilitation are required to reduce long-term disability and socioec… Show more

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Cited by 41 publications
(38 citation statements)
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“…On a final note, in light of the diversity of languages in tDCS/aphasia protocols 63 , it is interesting to consider the findings of recent neuro-linguistic studies which contend that language processing is activated in differing brain regions among speakers of languages that are structurally or morphologically dissimilar (e.g., Mandarin or Hebrew, compared with English, for example) 8688 . Future tDCS-aphasia studies may therefore wish to compare tDCS montage, polarity and outcomes across linguistically disparate languages, as well as in bilingual versus monolingual speakers.…”
Section: Discussionmentioning
confidence: 99%
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“…On a final note, in light of the diversity of languages in tDCS/aphasia protocols 63 , it is interesting to consider the findings of recent neuro-linguistic studies which contend that language processing is activated in differing brain regions among speakers of languages that are structurally or morphologically dissimilar (e.g., Mandarin or Hebrew, compared with English, for example) 8688 . Future tDCS-aphasia studies may therefore wish to compare tDCS montage, polarity and outcomes across linguistically disparate languages, as well as in bilingual versus monolingual speakers.…”
Section: Discussionmentioning
confidence: 99%
“…Unlike TMS, tDCS uses a low-intensity current of 1–2 mA to modulate (excite or inhibit) neuronal activity 63 . It has been explored in stroke rehabilitation as a method for encouraging brain plasticity, with results often lasting beyond the initial period of stimulation 62 .…”
Section: Tdcs For Aphasia Rehabilitationmentioning
confidence: 99%
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“…Recent years have seen considerable interest in the clinical use of noninvasive brain stimulation (NIBS), including transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES) (Hummel et al, 2005; Dayan et al, 2013; Fox et al, 2013; Dunlop et al, 2016; Otal et al, 2016). One promising avenue of research that advances towards minimizing interindividual differences in patients’ responses to NIBS integrates brain imaging data, particularly functional and structural brain connectivity, to provide personalized, guided stimulation in clinical contexts (Fox et al, 2013; Dunlop et al, 2016; Otal et al, 2016).…”
mentioning
confidence: 99%
“…One promising avenue of research that advances towards minimizing interindividual differences in patients’ responses to NIBS integrates brain imaging data, particularly functional and structural brain connectivity, to provide personalized, guided stimulation in clinical contexts (Fox et al, 2013; Dunlop et al, 2016; Otal et al, 2016). However, integrating imaging datasets into neuronavigation systems while simultaneously searching for the optimal stimulation site(s) in the clinic is a time-consuming process which requires operator training and may not be well-tolerated by some neurological and neuropsychiatric patient populations.…”
mentioning
confidence: 99%