Opposite changes in morphometric similarity of medial reward and lateral non-reward orbitofrontal cortex circuits in obesity

Dong, Debo; Chen, Ximei; Li, Wei; Gao, Xiao; Wang, Yulin; Zhou, Feng; Eickhoff, Simon B.; Chen, Hong

doi:10.1016/j.neuroimage.2024.120574

Cited by 6 publications

(1 citation statement)

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“…A meta-analysis found that people with obesity have lower execution ability than normal-weight people, with reduced inhibition control, working memory, and cognitive flexibility [4]. Besides reduced executive function, people with obesity also show reduced brain volume [18,19], morphometric similarity [20], and changed functional connectivity in the resting state [21,22].…”

Section: Introductionmentioning

confidence: 99%

Electrophysiological Characteristics of Inhibitive Control for Adults with Different Physiological or Psychological Obesity

Guo,

Wan,

Lian

et al. 2024

Nutrients

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Individuals exhibiting high scores on the fatness subscale of the negative-physical-self scale (NPSS-F) are characterized by heightened preoccupation with body fat accompanied by negative body image perceptions, often leading to excessive dieting behaviors. This demographic constitutes a considerable segment of the populace in China, even among those who are not obese. Nonetheless, scant empirical inquiries have delved into the behavioral and neurophysiological profiles of individuals possessing a healthy body mass index (BMI) alongside elevated NPSS-F scores. This study employed an experimental paradigm integrating go/no-go and one-back tasks to assess inhibitory control and working memory capacities concerning food-related stimuli across three adult cohorts: those with normal weight and low NPSS-F scores, those with normal weight and high NPSS-F scores, and individuals classified as obese. Experimental stimuli comprised high- and low-caloric-food pictures with concurrent electroencephalogram (EEG) and photoplethysmogram (PPG) recordings. Individuals characterized by high NPSS-F scores and normal weight exhibited distinctive electrophysiological responses compared to the other two cohorts, evident in event-related potential (ERP) components, theta and alpha band oscillations, and heart rate variability (HRV) patterns. In essence, the findings underscore alterations in electrophysiological reactivity among individuals possessing high NPSS-F scores and a healthy BMI in the context of food-related stimuli, underscoring the necessity for increased attention to this demographic alongside individuals affected by obesity.

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