Optic nerve head injury and optical coherence tomography angiography

Ma, Xiaoli; Hua, Rui

doi:10.21037/qims-20-1218

Cited by 2 publications

(1 citation statement)

References 25 publications

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“…Perhaps differences in the vascularization of the central retina and ONH should be considered. First, the surface of the optic nerve disc is supplied by the capillaries of the central retinal artery [ 32 ]. Second, the retinal ganglion cell axons in the peripapillary layer of nerve fibers are vascularized by a separate network of capillaries originating from the adjacent arterioles.…”

Section: Discussionmentioning

confidence: 99%

Optical Coherence Tomography Angiography Assessment of the Optic Nerve Head in Patients Hospitalized Due to COVID-19 Bilateral Pneumonia

Kal,

Brzdęk,

Zarębska-Michaluk

et al. 2024

Medicina

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Background and objectives: We aimed to investigate changes in the radial peripapillary capillary (RPC) network using optical coherence tomography angiography (OCTA) in patients who recovered from coronavirus disease 2019 (COVID-19). Materials and Methods: This was a prospective study of patients hospitalized due to COVID-19 bilateral pneumonia between March and May 2021. The control group included healthy individuals matched for age and sex. Two months after discharge, the patients underwent ophthalmological examination, including optical coherence tomography (OCT) imaging. The RPC network and retinal nerve fiber layer (RNFL) of the optic disc (RNFL optic disc) were automatically evaluated and compared between the study groups. Additionally, the RPC parameters were compared between the men and women in the COVID-19 group, and correlations between the RPC and RNFL optic disc parameters were assessed. Results: A total of 63 patients (120 eyes) with bilateral pneumonia caused by severe acute respiratory syndrome coronavirus 2 infection were examined. No ophthalmic symptoms were reported by the patients. No significant differences were observed in the RPC parameters between the patients from the COVID-19 group and the 43 healthy controls. Moreover, the RPC parameters did not differ between the men and women in the COVID-19 group. A positive correlation was found between the RPC and RNFL optic disc parameters in the COVID-19 patients (p < 0.001). Conclusions: No changes in the RPC network were observed among the patients with COVID-19 bilateral pneumonia in the early period after hospital discharge. However, a longer follow-up is needed to monitor COVID-19–related changes in the microvasculature of the optic nerve head.

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Section: Discussionmentioning

confidence: 99%