Optical Coherence Tomography for Quantitative Diagnosis in Nasopharyngeal carcinoma

Abstract

Abstract:We tried to quantitatively diagnose the intrinsic differences in the optical properties of nasopharyngeal carcinoma from normal tissue by optical coherence tomography. The scattering coefficients and anisotropies are extracted by fitting the average a-scan attenuation curves based on the multiple scatter effect. The median scattering coefficients of epithelium are 2.2 mm −1 (IQR 1.5 to 2.5 mm −1 ) for normal versus 3.8 mm −1 (IQR 2.0 to 3.3 mm −1 ) for cancer tissue; of lamina propria are 2.9 mm −1 (IQR 1.5 to 2.5 mm −1 ) for normal versus 1.