Optical coherence tomography’s current clinical medical and dental applications: a review

Ali, Saqib; Gilani, Saqlain Bin Syed; Shabbir, Juzer; Almulhim, Khalid S.; Bugshan, Amr; Farooq, Imran

doi:10.12688/f1000research.52031.1

Cited by 16 publications

(9 citation statements)

References 84 publications

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“…On the OCT image, hypomineralization appears white on a gray background, by increasing the dispersion signal [42]. This is in contrast to the radiolucent appearance of hypomineralization on the radiological examinations [43,44]. Therefore, OCT allows the clear identification of the hypomineralized enamel even at the early stage [30], as well as the extent of the defect, both in area and in depth [44].…”

Section: Discussionmentioning

confidence: 99%

Applications of Optical Coherence Tomography in the Diagnosis of Enamel Defects

et al. 2022

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Developmental defects of enamel (DDEs) are deviations from the normal appearance in terms of the quantity and quality of tooth enamel. They may be genetic or acquired. The most important DDEs are hypomineralization and hypoplasia. The aim of this study was to produce “in vivo” DDE in Wistar rats by administering amoxicillin to pregnant females and to highlight these lesions after sacrifice of the pups by macroscopic and microscopic examination and optical coherence tomography (OCT). Amoxicillin (100 mg/kg) was administered to two pregnant Wistar female rats for the production of DDEs. When the pups were 2 months old, they were sacrificed, and their jaws were harvested together with their teeth. The jaws were examined macroscopically, microscopically, and by OCT. Following the macroscopic and microscopic examination, it was established that four pups had a total of 42 DDE lesions. At the OCT examination, the hypomineralization was characterized by an intense, inhomogeneous OCT signal, and the hypoplasia was characterized by the absence of the signal. Administration of amoxicillin to pregnant females of Wistar rats resulted in DDEs in their offspring. The OCT examination confirmed the presence of these lesions in the teeth of rat pups.

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Section: Discussionmentioning

confidence: 99%

Applications of Optical Coherence Tomography in the Diagnosis of Enamel Defects

et al. 2022

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“…Radiography cannot distinguish active caries from arrested caries [ 24 , 66 ]. Moreover, enamel and dentin could be easily differentiated on OCT images due to their different optical properties [ 12 ]. OCT shows promising results in pediatric dentistry for incipient caries detection due to its real-time and noninvasive nature [ 67 ].…”

Section: Methodsmentioning

confidence: 99%

“…An 8 μ m axial resolution and a 2 μ m axial and lateral resolution are reported as state of the art. OCT is fast, repeatable, and well tolerated by patients [ 12 – 14 ]. It has several potential applications in oncology.…”

Section: Introductionmentioning

confidence: 99%

Oral Cancer Screening by Artificial Intelligence-Oriented Interpretation of Optical Coherence Tomography Images

Ramezani

Tofangchiha

2022

Radiology Research and Practice

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Early diagnosis of oral cancer is critical to improve the survival rate of patients. The current strategies for screening of patients for oral premalignant and malignant lesions unfortunately miss a significant number of involved patients. Optical coherence tomography (OCT) is an optical imaging modality that has been widely investigated in the field of oncology for identification of cancerous entities. Since the interpretation of OCT images requires professional training and OCT images contain information that cannot be inferred visually, artificial intelligence (AI) with trained algorithms has the ability to quantify visually undetectable variations, thus overcoming the barriers that have postponed the involvement of OCT in the process of screening of oral neoplastic lesions. This literature review aimed to highlight the features of precancerous and cancerous oral lesions on OCT images and specify how AI can assist in screening and diagnosis of such pathologies.

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“…Thus, non-invasive tools to assess, in real-time, the in vitro viability, metabolic activity and structures are necessary for regenerative medicine [ 28 , 29 ]. OCT, routinely used in ophthalmology, is an effective imaging technique that reveals tissue morphology without additional tissue fixation and labelling [ 30 , 31 ]. Despite a limited penetration depth (2–3 mm), OCT has a high-scan speed and allows high-resolution cross-sectional imaging, thereby providing real-time data [ 32 ].…”

Section: Introductionmentioning

confidence: 99%