Optical microresonators as single-particle absorption spectrometers

Heylman, Kevin D.; Thakkar, Niket; Horak, Erik H.; Quillin, Steven C.; Cherqui, Charles; Knapper, Kassandra A.; Masiello, David J.; Goldsmith, Randall H.

doi:10.1038/nphoton.2016.217

Cited by 163 publications

(231 citation statements)

References 55 publications

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“…The coupling regimes for periodic arrangements of identical plasmonic particles along the equator of a WGM have been treated theoretically [112], and singleparticle absorption spectroscopy with hybrid WGM-plasmonic devices has been conducted experimentally [113] (Figure 16). For the latter, dense sets of Fano resonances could make modalities like coherent anti-Stokes Raman spectroscopy [114] within reach.…”

Section: Optoplasmonic Sensors: Single-molecule Detectionmentioning

confidence: 99%

Advances in optoplasmonic sensors – combining optical nano/microcavities and photonic crystals with plasmonic nanostructures and nanoparticles

et al. 2017

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Nanophotonic device building blocks, such as optical nano/microcavities and plasmonic nanostructures, lie at the forefront of sensing and spectrometry of trace biological and chemical substances. A new class of nanophotonic architecture has emerged by combining optically resonant dielectric nano/microcavities with plasmonically resonant metal nanostructures to enable detection at the nanoscale with extraordinary sensitivity. Initial demonstrations include single-molecule detection and even single-ion sensing. The coupled photonic-plasmonic resonator system promises a leap forward in the nanoscale analysis of physical, chemical, and biological entities. These optoplasmonic sensor structures could be the centrepiece of miniaturised analytical laboratories, on a chip, with detection capabilities that are beyond the current state of the art. In this paper, we review this burgeoning field of optoplasmonic biosensors. We first focus on the state of the art in nanoplasmonic sensor structures, high quality factor optical microcavities, and photonic crystals separately before proceeding to an outline of the most recent advances in hybrid sensor systems. We discuss the physics of this modality in brief and each of its underlying parts, then the prospects as well as challenges when integrating dielectric nano/microcavities with metal nanostructures. In Section 5, we hint to possible future applications of optoplasmonic sensing platforms which offer many degrees of freedom towards biomedical diagnostics at the level of single molecules.

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Section: Optoplasmonic Sensors: Single-molecule Detectionmentioning

confidence: 99%

Advances in optoplasmonic sensors – combining optical nano/microcavities and photonic crystals with plasmonic nanostructures and nanoparticles

et al. 2017

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“…8b and 8c. [68][69][70] In the experiment, mode shift signals are recorded in real time when scanning the pump laser beam spatially on the top surface of the resonators, which create a thermal shift image. Experimentally, large area thermal mappings of a normal silica toroid on silicon pillar (left) and an all-glass toroid (right) are taken to compare the background noises (Fig.…”

Section: Photothermal Absorption Spectroscopy and Imagingmentioning

confidence: 99%

“…Besides, thermal scanning technique has been demonstrated to reduce the noise of frequency comb and optical solitons 65 . Moreover, thermal locking 66,67 and thermal imaging techniques [68][69][70] have also been developed by taking advantages of thermal instabilities and thermal absorption, respectively, which will find broad applications in sensing, microscopy, and spectroscopy.…”

Section: Introductionmentioning

confidence: 99%

Optothermal dynamics in whispering-gallery microresonators

2020

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Optical whispering-gallery-mode microresonators with ultrahigh quality factors and small mode volumes have played an important role in modern physics. They have been demonstrated as a diverse platform for a wide range of photonics applications, such as nonlinear optics, optomechanics, quantum optics, and information processing. Thermal behaviors induced by power buildup in resonators or environmental perturbations are ubiquitous in high-quality-factor whispering-gallery-mode resonators and have played an important role in their operation for various applications. Here in this review, we discuss the mechanisms of laser field induced thermal nonlinear effects, including thermal bistability and thermal oscillation. With the help of the thermal bistability effect, optothermal spectroscopy and optical non-reciprocity have been demonstrated. On the other hand, by tuning the temperature of the environment, the resonant mode frequency will shift, which could also be used for thermal sensing/tuning applications. Thermal locking technique and thermal imaging mechanisms are discussed briefly. Last, we review some techniques to realize thermal stability in a high-quality-factor resonator system.

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“…A sensor that can detect a minute quantity of exosomes can potentially determine the existence and progression of a tumor based upon the circulation of blood without the need to find and access the tumor. Recently, a similar frequency-locking scheme was combined with absorption spectroscopy to measure the absorption spectra of gold nanorods in air on a microtoroid [98]. …”

Section: Recent Developments In Biological and Chemical Sensingmentioning

confidence: 99%

Label-Free Biological and Chemical Sensing Using Whispering Gallery Mode Optical Resonators: Past, Present, and Future

2017

Sensors

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Sensitive and rapid label-free biological and chemical sensors are needed for a wide variety of applications including early disease diagnosis and prognosis, the monitoring of food and water quality, as well as the detection of bacteria and viruses for public health concerns and chemical threat sensing. Whispering gallery mode optical resonator based sensing is a rapidly developing field due to the high sensitivity and speed of these devices as well as their label-free nature. Here, we describe the history of whispering gallery mode optical resonator sensors, the principles behind detection, the latest developments in the fields of biological and chemical sensing, current challenges toward widespread adoption of these devices, and an outlook for the future. In addition, we evaluate the performance capabilities of these sensors across three key parameters: sensitivity, selectivity, and speed.

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Optical microresonators as single-particle absorption spectrometers

Cited by 163 publications

References 55 publications

Advances in optoplasmonic sensors – combining optical nano/microcavities and photonic crystals with plasmonic nanostructures and nanoparticles

Advances in optoplasmonic sensors – combining optical nano/microcavities and photonic crystals with plasmonic nanostructures and nanoparticles

Optothermal dynamics in whispering-gallery microresonators

Label-Free Biological and Chemical Sensing Using Whispering Gallery Mode Optical Resonators: Past, Present, and Future

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