In today’s era of innovation and the vigorous development of the digital economy, globalization and antiglobalization are intertwined, and cultural dissemination and integration are gradually expanding the influence and scope of the era; the revival and inheritance of traditional culture have become increasingly important in our country. The development of the creative industry is becoming more and more vigorous and full of vitality. Based on deep learning algorithms, this paper studies the cultural and creative design of Dunhuang frescoes in the Western Xia period. This paper analyzes the shortcomings of the current cultural and creative market and the characteristics of high-quality cultural and creative design, analyzes the principles of cultural and creative design of cultural relics, etc., proposes a generative confrontation network model, establishes a modern cultural and creative design model, and provides a three-level cultural model for cultural and creative design. The process is analyzed. In the evaluation and analysis of users, it is concluded that the integration of traditional culture design factor score is 4.80, conforming to the modern aesthetic situation is 4.63, conforming to the user’s expectation of “elegant” is 4.73, and the comprehensive score is 4.72.