Abstract-According to the nonlinear, time-varying variable, large lag and other properties of air handle system, the improved ant colony algorithm is adopted to optimize the air handle system energy consumption. First, mathematical model of wind system of central air conditioning energy consumption is established for improved ant colony algorithm to optimize the model of energy consumption minimization.The improved ant colony algorithm solves the defect of directly deal with continuous optimization problem using ant colony algorithm by discretizing the solution space of continuous function. The experimental results show that, the improved ant colony algorithm can be successfully used in air handle system of HVAC, and has achieved an execellent effect of energy-saving.