OPTIMASI KOMPOSISI TWEEN 80 DAN SPAN 80 SEBAGAI EMULGATOR DALAM REPELAN MINYAK ATSIRI DAUN SERE (Cymbopogon citratus (D.C) Stapf) TERHADAP NYAMUK Aedes aegypti BETINA PADA BASIS VANISHING CREAM DENGAN METODE SIMPLEX LATTICE DESIGN

Nurlaela, Endah; Sugihartini, Nining; Ikhsanudin, Azis

doi:10.12928/pharmaciana.v2i1.652

Cited by 8 publications

(8 citation statements)

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“…The dispersion test refers to [13]. A total of 500 mg of lotion is weighed and placed on a glass covered with another glass over the gel mass and left for 1 minute.…”

Section: Dispersion Testmentioning

confidence: 99%

Characteristics of mosquito-repellent lotion made from pineapple peel waste

Dewi,

Johan,

Hasnah

et al. 2024

BIO Web Conf.

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Pineapple peel can be used as a natural ingredient in making mosquito-repellent lotion because it contains many secondary metabolite compounds, including saponins, tannins, flavonoids, alkaloids, steroids, and essential oils. The research aims to obtain the right concentration of pineapple peel extract on the characteristics of the mosquito-repellent lotion produced. The method used was an experimental method with a Completely Randomized Design (CRD) consisting of five treatments (2%, 3%, 4%, 5%, and 6% pineapple peel extract) with three replications to obtain 15 experimental units. The selected treatment was LN2 (lotion with a 3% concentration of pineapple peel extract), providing homogeneous physical characteristics of the lotion preparation, a pH value of 7.93, a spread ability value of 5.50 cm, a viscosity value of 3829.51 cP, and mosquito protection power 80.16%. The descriptive organoleptic assessment showed that the color of the lotion was yellowish brown, slightly scented with citronella, and slightly sticky in texture, and the panelists liked the hedonic evaluation of color and texture. The panelists little appreciated the hedonic aroma.

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“…The dispersion test refers to [13]. A total of 500 mg of lotion is weighed and placed on a glass covered with another glass over the gel mass and left for 1 minute.…”

Section: Dispersion Testmentioning

confidence: 99%

Characteristics of mosquito-repellent lotion made from pineapple peel waste

Dewi,

Johan,

Hasnah

et al. 2024

BIO Web Conf.

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“…Keuntungan metode ini adalah mudah dan tidak perlu pemanasan sehingga kecil kemungkinan bahan alam menjadi rusak atau terurai. 11 Sediaan gel harus memenuhi syarat uji sifat fisik dan uji stabilitas fisik sediaan gel yang baik. Berdasarkan hasil pengamatan, menunjukan bahwa setiap fomula memiliki konsistensi cukup kental dan meningkat dari F1, F2 dan F3.…”

Section: Diskusiunclassified

Formulation of Gel Hand Sanitizer of Nagasari Leaf Extract (Mesua ferrea L.)

Suhesti

Rohman²,

Sunarto³

2022

IJPST

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Nagasari (Mesua ferrea L.) is one of the biodiversity to be developed as an antiseptic preparation. These plants are known to contain flavonoid compounds, tannins, and terpenoids that act as antibacterial. Hand sanitizer gel preparations can increase the effectiveness of topically. The physical properties of a good gel depend on a gelling agent, one of which is HPMC. The purpose of this study was to determine the effect of variations in HPMC levels on physical properties and antibacterial activity. Gels were prepared with various HPMC levels of 1%, 2%, and 3%. The gel was tested for physical properties and stability. All formulas produced preparations that met the requirements for good physical properties and stability. Testing of antibacterial activity against Staphylococcus aureus showed that an increase in HPMC levels could decrease the ability to release the active substance of the preparation. The diameter of the inhibition zone obtained was 10.0 mm (HPMC 1%); 9.5 mm (2% HPMC) and 8.0 mm (3% HPMC). Increasing the concentration of HPMC will increase the viscosity and adhesion but decrease the spreadability. The three formulas had antibacterial activity against Staphylococcus aureus with moderate criteria.Keywords: Extract of nagasari leaf, Gel, HPMC, Staphylococcus aureus

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“…Pada preformulasi ini menggunakan bahan-bahan diantaranya Polysorbate (Tween 80), Sorbitan Monooleate (Span 80), Air, Mineral Oil. Tween 80 dan Span 80 merupakan campuran surfaktan non ionic yang sistem kerjanya sebagai bahan pengemulsi adalah menjaga keseimbangan antara gugus hidrofil dan lipofil (Nurlaela, Sugihartini, & Ikhsanudin, 2012).…”

Section: Pembahasanunclassified

Studi Preformulasi Sediaan Farmasi Dengan Software Exc-Sol

Wicita

Pomalingo²,

Nurmalasari³

et al. 2021

JECP

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Preformulasi merupakan tahap awal dalam rangkaian proses pembuatan sediaan farmasi yang berpusat pada sifat-sifat fisika kimia zat aktif serta interaksi dengan komponen lain yang dapat mempengaruhi penampilan obat. Salah satu tahap dalam preformulasi ialah melihat interaksi atau ketidakcampuran bahan-bahan dalam formulasi. Ketidakcampuran atau inkompatibilitas bahan tambahan yang digunakan dapat ditentukan dengan menggunakan software EXC-Sol. Selain inkompatibilitas, software ini dapat menganilisis kebutuhan surfaktan atau emulgator sesuai HLB yang dibutuhkan. Hasil percobaan menunjukkan bahwa pada formulasi pertama yaitu Carbinoxamini Elixir terdapat inkompatibilitas dengan ditandai warna merah pada hasil analisis dan dapat diperoleh jumlah masing-masing bahan pengemulsi dengan menggunakan nilai HLB pada formulasi kedua yaitu emulsi kurkumin. Kata Kunci: Preformulasi, EXC-Sol, Inkompatibilitas, HLB

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OPTIMASI KOMPOSISI TWEEN 80 DAN SPAN 80 SEBAGAI EMULGATOR DALAM REPELAN MINYAK ATSIRI DAUN SERE (Cymbopogon citratus (D.C) Stapf) TERHADAP NYAMUK Aedes aegypti BETINA PADA BASIS VANISHING CREAM DENGAN METODE SIMPLEX LATTICE DESIGN

Abstract: AbstrakPenyakit demam berdarah dengue (DBD)

Cited by 8 publications

References 0 publications

Characteristics of mosquito-repellent lotion made from pineapple peel waste

Characteristics of mosquito-repellent lotion made from pineapple peel waste

Formulation of Gel Hand Sanitizer of Nagasari Leaf Extract (Mesua ferrea L.)

Studi Preformulasi Sediaan Farmasi Dengan Software Exc-Sol

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