Optimierung von Blutgasanalysen auf der Intensivstation

Kieninger, Martin; Zech, Nina; Mulzer, Y; Bele, Sylvia; Seemann, Milena; Künzig, H. J.; Schneiker, André; Gruber, Michael

doi:10.1007/s00101-015-0024-8

Cited by 5 publications

(2 citation statements)

References 9 publications

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“…The sample extraction procedure should be rigorous since air aspiration or bubble formation in blood gas syringes can significantly alter blood gas parameters [ 26 ]. Exposure of a blood gas sample to air would typically result in an elevation or drop in p O 2 to 150 mmHg and perhaps a decrease in p CO 2 along with an increase in pH due to the loss of carbonic acid at prolonged exposure [ 20 ].…”

Section: Discussionmentioning

confidence: 99%

Stability of pH, Blood Gas Partial Pressure, Hemoglobin Oxygen Saturation Fraction, and Lactate Concentration

et al. 2020

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Background The storage temperature and time of blood gas samples collected in syringes constitute preanalytical variables that could affect blood gas or lactate concentration measurement results. We analyzed the effect of storage temperature and time delay on arterial or venous blood gas stability related to pH, partial pressure of carbon dioxide ( p CO 2 ) and oxygen ( p O 2 ), hemoglobin oxygen saturation ( s O 2 ), and lactate concentration. Methods In total, 1,200 arterial and venous blood sample syringes were analyzed within 10 minutes of collection. The samples were divided into different groups to determine parameter stability at 25, 4–8, and 0–3.9°C and at different storage times, 60, 45, 30, and 15 minutes. Independent sample groups were used for each analysis. Percentage deviations were calculated and compared with acceptance stability limits (1.65× coefficient of variation). Additionally, sample group sub analysis was performed to determine whether stability was concentration-dependent for each parameter. Results The pH was stable over all storage times at 4–8 and 0–3.9°C and up to 30 minutes at 25°C. p CO 2 was stable at ≤60 minutes at all temperatures. p O 2 was stable for 45 minutes at 0–3.9°C, and s O 2 was stable for 15 minutes at 25°C and for ≤60 minutes at 0–3.9°C. Lactate concentration was stable for 45 minutes at 0–3.9°C. Subanalysis showed that stability was concentration-dependent. Conclusions The strictest storage temperature and time criteria (0–3.9°C, 45 minutes) should be adopted for measuring pH, p CO 2 , p O 2 , s O 2 , and lactate concentration in blood gas syringes.

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Section: Discussionmentioning

confidence: 99%

Stability of pH, Blood Gas Partial Pressure, Hemoglobin Oxygen Saturation Fraction, and Lactate Concentration

et al. 2020

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“…Die Blutgasanalyse (BGA) ist eine wesentliche und etablierte Methode des Point-of-Care-Testings (POCT) und erlaubt u. a. die Kontrolle des Sauerstoff-und Kohlendioxidgehalts des Blutes zur Steuerung der Beatmungsparameter. Die in der heutigen Zeit verfügbaren modernen Analysegeräte erlauben zudem die Bestimmung der Sauerstoffsättigung zur Beurteilung der Sauerstoffversorgung des Organismus, die Messung von Hämoglobin und Hämatokrit zur Steuerung der Blutersatztherapie, die Bestimmung von Elektrolyten, die Messung des Laktatspiegels, die Beurteilung der Säure-Basen Homöostase sowie die Kontrolle des Blutzuckerspiegels [7].…”

Section: Perioperative Analyse Der Blutgase Hämoglobin Und Hämatokritunclassified

Relevante Eckpunkte der intraoperativen anästhesiologischen Diagnostik

et al. 2016

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The main focus of surgeons and anaesthesiologists during a surgical procedure is on safety and optimal treatment of the patient. Within the scope of interdisciplinary collaboration, the intraoperative communication between surgeons and anaesthesiologists is the basis of case-, findings- and surgery-phases-adapted patient management. The perioperative monitoring of patients and the implementation of diagnostic measures by anaesthesiologists are essential for optimal patient management. The results of the examinations may significantly determine the course of surgery. Therefore, it is important for surgeons to be familiar with the relevant intraoperative diagnostic measures.

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