Optimization and comparison of balloon-based partial breast brachytherapy using a single source, a standard plan line source, and both forward and inverse planned multilumen techniques

Eyre, K.; Whitney, Diane; Mukesh, Mukesh; Wilson, Charles B.; Coles, Charlotte E.

doi:10.1016/j.brachy.2012.03.010

Cited by 4 publications

(4 citation statements)

References 19 publications

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“…Eyre et al . [24] published a study directly comparing four dosimetric techniques for balloon-based partial breast brachytherapy: single source, standard line source, and both forward planned and inverse planned multi-lumen (ML). They presented a standard line source plan to be used in a single catheter or as a starting point for forward planned ML.…”

Section: Discussionmentioning

confidence: 99%

“…Authors concluded that multiple sources in a single catheter improved coverage at catheter ends, whereas ML can further improve coverage and reduce dose to organs at risk. Using a standard line source as a starting point for forward planning ML means increase in planning time is kept to a minimum, making it a practicable option for centers without inverse planning software [24]. Arthur et al .…”

Section: Discussionmentioning

confidence: 99%

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Can we improve the dose distribution for single or multi-lumen breast balloons used for Accelerated Partial Breast Irradiation?

Skowronek

Bielęda²,

Łaski³

et al. 2013

jcb

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PurposeThe aim of the study was to verify dose distribution parameters for multi-lumen, and artificially created single-lumen balloon applicator used for the same patient with two optimization algorithms: inverse planning simulated annealing (IPSA) and dose point optimization with distance option.Material and methodsGroup of 24 patients with multi-lumen balloon applied were investigated. Each patient received 10 fractions of 3.4 Gy (2 fractions daily). For every patient, four treatment plans were prepared. Firstly, for five-lumen balloon optimized with IPSA algorithm and optimization parameters adjusted for each case. Secondly, for the same applicator optimized with dose point optimization and distant option. Two other plans were prepared for single-lumen applicator, created by removing four peripheral lumens, optimized with both algorithms.ResultsThe highest D95 parameter was obtained for plans optimized with IPSA algorithm, mean value 99.3 percent of prescribed dose, and it was significantly higher than plans optimized with dose point algorithm (mean = 83.50%, p < 0.0001), IPSA single-lumen balloon plan (mean = 83.50%, p = 0.0037) and optimized to dose point single-lumen balloon (mean = 85.51%, p < 0.0001). There were no statistically significant differences concerning maximum doses distributed to skin surface for neither application nor optimization method. Volumes receiving 200% of prescribed dose in PTV were higher for multi-lumen balloon dose point optimized plans (mean = 8.78%), than for other plans (IPSA multi-lumen balloon plan: mean = 7.37%, p < 0.0001, single-lumen IPSA: mean = 7.20%, p < 0.0001, single-lumen dose point: mean = 7.19%, p < 0.0001).ConclusionsBasing on performed survey, better dose distribution parameters are obtained for patients with multi-lumen balloon applied and optimized using IPSA algorithm with individualized optimization parameters.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Can we improve the dose distribution for single or multi-lumen breast balloons used for Accelerated Partial Breast Irradiation?

Skowronek

Bielęda²,

Łaski³

et al. 2013

jcb

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“…Dosimetric comparisons between balloon brachytherapy devices have shown that multilumen balloons like the Contura multi-lumen (Hologic) or the MammoSite multi-lumen balloon applicators provide superior dose coverage compared with single lumen balloon devices, particularly at the ends of the catheters, where anisotropy can lead to reduced dose [17,[67][68]. When compared with superficial photon therapy, HDR brachytherapy provides potential for a higher dose at 1cm without exceeding the maximum dose at the lumpectomy surface [17].…”

Section: • • Cost-effectivenessmentioning

confidence: 99%

Techniques for Intraoperative Radiation Therapy for Early-Stage Breast Carcinoma

et al. 2015

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Intraoperative radiation therapy (IORT) is a method of accelerated partial breast irradiation developed to replace other longer courses of radiotherapy with a single radiation session administered at the time of breast-conserving surgery. The purpose of this review is to summarize the advantages and disadvantages of breast IORT techniques that are currently available, as well to consider potential alternative techniques for breast IORT or ultra-short course breast radiotherapy. Furthermore, we highlight the published outcomes for the IORT treatment approaches including: electron therapy, superficial photon therapy and other techniques. Potential future directions of IORT are explored including novel IORT techniques utilizing intraoperative brachytherapy with in-room imaging and rapid treatment planning.

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“…The addition of multiple catheters through the balloon has allowed for radial dose variation and optimization, and has made balloon-based brachytherapy more customizable. 55 , 58 , 59 …”

Section: Brachytherapy-specific Considerationsmentioning

confidence: 99%

Accelerated partial breast irradiation with brachytherapy: patient selection and technique considerations

Trifiletti

Romano

Showalter

et al. 2015

BCTT

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Accelerated partial breast irradiation (APBI) through breast brachytherapy is a relatively recent development in breast radiotherapy that has gained international favor because of its reduction in treatment duration and normal tissue irradiation while maintaining favorable cancer-specific and cosmetic outcomes. Despite the fact that several large national trials have not reported final results yet, many providers are currently offering APBI to select patients and APBI is listed as a treatment option for selecting patients in the National Comprehensive Cancer Network guidelines. Multiple consensus guidelines exist in selecting patients for APBI, some with conflicting recommendations. In this review, the existing patient selection guidelines are reported, compared, and critiqued, grouping them in helpful subcategories. Unique patient and technical selection factors for APBI with brachytherapy are explored.

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Optimization and comparison of balloon-based partial breast brachytherapy using a single source, a standard plan line source, and both forward and inverse planned multilumen techniques

Cited by 4 publications

References 19 publications

Can we improve the dose distribution for single or multi-lumen breast balloons used for Accelerated Partial Breast Irradiation?

Can we improve the dose distribution for single or multi-lumen breast balloons used for Accelerated Partial Breast Irradiation?

Techniques for Intraoperative Radiation Therapy for Early-Stage Breast Carcinoma

Accelerated partial breast irradiation with brachytherapy: patient selection and technique considerations

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