Optimization of extraction method to obtain a phenolic compounds-rich extract from Moringa oleifera Lam leaves

Rodríguez‐Pérez, Celia; Quirantes-Piné, Rosa; Fernández‐Gutiérrez, Alberto; Segura‐Carretero, Antonio

doi:10.1016/j.indcrop.2015.01.002

Cited by 226 publications

(154 citation statements)

References 34 publications

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“…Evaluated using the Folin–Ciocalteu reagent, TPC of the ME extracted by ethanol:water (70:30) in this study was about 24.4 mg GAE/g dry leaves. This result was comparable to that found by (Rodríguez‐Pérez et al, ) by the same extract and which was about 24.3 mg GAE/g dry leaf. Higher TPC value could be obtained by methanol as extract (Anwar et al, ; Rodríguez‐Pérez et al, ), but ethanol was selected as the solvent because of its food security character.…”

Section: Resultssupporting

confidence: 90%

“…M. oleifera has been authorized as a new food resource by Ministry of Health of China in 2012 (Zheng, Zhang, & Wu, ). Containing a great amount of phenolic acids and flavonoids, M. oleifera extract has been reported to possess significant antioxidant activity (Rodríguez‐Pérez, Mendiola, Quirantes‐Piné, Ibáñez, & Segura‐Carretero, ; Rodríguez‐Pérez, Quirantes‐Piné, Fernández‐Gutiérrez, & Segura‐Carretero, ). The M. oleifera leaves extract has been used for the treatment of bronchitis, ulcers, malaria, fever, diabetes, and so on (Coz‐Bolanos et al, ; Patel, Thakur, Chandy, & Manigauha, ; Sosa‐Gutierrez et al, ).…”

Section: Introductionmentioning

confidence: 99%

“…The M. oleifera leaves extract has been used for the treatment of bronchitis, ulcers, malaria, fever, diabetes, and so on (Coz‐Bolanos et al, ; Patel, Thakur, Chandy, & Manigauha, ; Sosa‐Gutierrez et al, ). It has also been reported to have anti‐inflammatory and whitening effects and could be applied for cosmetics as natural ingredient (Rodríguez‐Pérez et al, ).…”

Section: Introductionmentioning

confidence: 99%

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Antioxidation activity of Moringa oleifera Lam. leaves extract on soybean oil during both storage and thermal treatment

Zhao

Lan

et al. 2019

J Food Process Preserv

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The effect of Moringa oleifera leaves extract (ME) on the oxidative stability of soybean oil was studied during 12 days accelerated storage (60°C) and 24 hr thermal treatment (105, 120, 150, and 180°C). Peroxide, p‐anisidine and TOTOX (total oxidation) value of soybean oil samples were determined. Results showed that ME had significant antioxidation effect on soybean oil in storage test. However, the antioxidation effect of ME decreased with the rising of the heating temperature. Additionally, synergistic effect in binary mixtures of ME with ascorbic acid, citric acid, and α‐T was tested. The mixture of 0.1% ME + 0.02% α‐T displayed a significant synergistic effect of 35.8%. Considering the safe application of M. oleifera for nutritional and therapeutic use, M. oleifera leaves extract can be used as an antioxidation in soybean oil. Practical applications Rich in phenolic acids and flavonoids, M. oleifera leaves extract exhibits significant antioxidant activity both in vitro and in vivo. ME has been widely used in medicine, functional food, cosmetics industries, and so on. The addition of ME in soybean oil significantly inhibited the oil oxidation, especially during storage process. These results demonstrated that ME with a high antioxidant activity could be used as an antioxidant in soybean oil.

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Section: Resultssupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Antioxidation activity of Moringa oleifera Lam. leaves extract on soybean oil during both storage and thermal treatment

Zhao

Lan

et al. 2019

J Food Process Preserv

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“…Their familiar fragmentation pattern includes the loss of the caffeic acid ( m / z 179) and hexose moiety ( m / z 161). Peak 36 was only found in the aerial part of G. trichosantha and from its MS/MS spectra, which includes fragments at m / z 191, 161, 127 and 135, and the data from the literature, it was assigned as caffeoylquinic acid. Compound 39 with a molecular formula C 15 H 18 O 8 , was only detected in G. orientalis and it was tentatively characterised as p ‐coumaroyl hexose based on its fragmentation pattern which has been described elsewhere .…”

Section: Resultsmentioning

confidence: 99%

Chemical fingerprint and bioactivity evaluation of Globularia orientalis L. and Globularia trichosantha Fisch. & C. A. Mey. using non‐targeted HPLC‐ESI‐QTOF‐MS approach

Rodríguez‐Pérez

Zengin

Segura‐Carretero

et al. 2018

Phytochemical Analysis

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Introduction In the quest for new sources of biologically‐active compounds, the chemical, and biological profiles of two Globularia species (G. trichosantha Fisch. & C. A. Mey and G. orientalis L.) were investigated. Methodology Chemical profiles were evaluated by high‐performance liquid chromatography coupled to electrospray ionisation and quadrupole time‐of‐flight mass spectrometry (HPLC‐ESI‐QTOF‐MS), as well as by their total phenolic, flavonoids, and phenolic acids contents. The antioxidant abilities of the investigated extracts were done using different assays including free radical scavenging [1,1‐diphenyl‐2‐picryl‐hydrazyl (DPPH) and 2,2′‐azino‐bis(3‐ethylbenzothiazoline‐6‐sulphonic acid (ABTS)], reducing power (cupric reducing antioxidant capacity and ferric reducing antioxidant power), phosphomolybdenum, and metal chelating. Inhibitory potential against key enzymes involved in neurodegenerative diseases (cholinesterases; AChE, and BChE), diabetes (α‐glucosidase and α‐amylase), hyperpigmentation (tyrosinase) and obesity (pancreatic lipase) were evaluated. Results Globularia trichosantha and G. orientalis extracts showed remarkable antioxidant properties, with the water extracts being a better source of antioxidant compounds. Both species showed remarkable inhibitory effects against the target enzymes. However, for both species, only the acetyl acetate and methanolic extracts were potent against cholinesterases and lipase. Conclusion HPLC‐ESI‐QTOF‐MS analysis revealed the presence of 107 compounds from G. trichosantha and G. orientalis, among which, 43 compounds have been preliminarily characterised for the first time from the Globulariaceae family. To date, this study can be considered as the most comprehensive research focused on the characterisation of G. trichosantha and G. orientalis. Results amassed from this study tend to show that these plants represent a rich source of biologically active compounds which can be further explored and validated for their therapeutic potential.

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“…This trend was also observed in the recovery of flavonoids with an increase of 18.3r this value. Rodríguez-Pérez et al [58] also reported an increase in the production of phenolic compounds from olefinic leaves by UAE (47 mg GAE/g DW) when compared to conventional extraction (27 mg GAE/g DW), reporting chlorogenic acid as the major compound.…”

Section: Comparison Against Conventional Methodsmentioning

confidence: 96%

Ultrasound Assisted Extraction for the Recovery of Phenolic Compounds from Vegetable Sources

Medina-Torres¹,

et al. 2017

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Vegetable sources and agro-industrial residues represent an important source of phenolic compounds that are useful in a wide range of applications, especially those with biological activities. Conventional techniques of phytochemical extraction have been associated with a high consumption of organic solvents that limits the application of bioactive extracts, leading to the implementation of novel extraction technologies using mechanisms such as Ultrasound Assisted Extraction (UAE). In the present review, an analysis of the involved variables in the extraction yield of phenolic compounds through UAE is presented, highlighting the advantages of this technology based on the results obtained in various optimized studies. A comparison with other technologies and a proposal of its possible application for agro industrial residues as raw material of phenolic compounds is also indicated. Finally, it is concluded that UAE is a technology that is placed within the area of Sustainable Chemistry since it promotes the use of renewable raw materials through the extraction of phenolic compounds, implementing the substitution of organic solvents with solvents that do not present toxic effects, lowering the energy consumption when compared to conventional methods and minimizing process times and temperatures, which is useful for the extraction of thermo-labile compounds.

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Optimization of extraction method to obtain a phenolic compounds-rich extract from Moringa oleifera Lam leaves

Cited by 226 publications

References 34 publications

Antioxidation activity of Moringa oleifera Lam. leaves extract on soybean oil during both storage and thermal treatment

Antioxidation activity of Moringa oleifera Lam. leaves extract on soybean oil during both storage and thermal treatment

Chemical fingerprint and bioactivity evaluation of Globularia orientalis L. and Globularia trichosantha Fisch. & C. A. Mey. using non‐targeted HPLC‐ESI‐QTOF‐MS approach

Ultrasound Assisted Extraction for the Recovery of Phenolic Compounds from Vegetable Sources

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