Optimization of flavonoid extraction from Passiflora quadrangularis leaves with sedative activity and evaluation of its stability under stress conditions

Echeverry, Sandra Milena; Medina, Hilbert I.; Costa, Geison Modesti; Aragón, Diana Marcela

doi:10.1016/j.bjp.2018.06.005

Cited by 19 publications

(16 citation statements)

References 17 publications

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“…Four putatively identified flavonoids and its derivatives which had similarly reported in Passiflora sp. namely isoquercitin, myricetin, isovitexin 2''-O-(6‴-(E)-P-Coumaroyl), Glucoside 4'-O-Glucoside, 3,6,3',4'-tetrahydroxyflavone are among the prominent metabolite markers [56,58]. The chemical marker of P. quadrangularis (vitexin-2"-O-xyloside) reported by Costa et al [59].…”

Section: Plos Onementioning

confidence: 98%

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Organic cultivation practices enhanced antioxidant activities and secondary metabolites in giant granadilla (Passiflora quadrangularis L.)

et al. 2021

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Passiflora quadrangularis L. belongs to the family Passifloraceae which bears larger fruit with edible juicy mesocarp and pulp known as a good source of phytochemicals. Cultivation and plant management practices are known to influence the phytochemical compositions of agricultural produce. This study aimed to examine the influence of the cultivation practices on the antioxidant activities and secondary metabolites of the organically and conventionally grown P. quadrangularis. Findings revealed organically treated P. quadrangularis plants showed enhancement in their antioxidant properties and secondary metabolites profiles. Among the plant parts, leaves of P. quadrangularis grown organically possessed higher antioxidant activities compared to the conventional in all assays evaluated. The antioxidant activities in the edible parts of the P. quadrangularis fruit have also been enhanced through organic cultivation with significantly higher total phenolic content and DPPH in mesocarp, and the pulp showed higher total flavonoid content, DPPH and FRAP. This observation is supported by a higher level of vitamins and secondary metabolites in the samples. The secondary metabolites profile showed mesocarps were phenolic rich, the pulps were flavonoids rich while leaves showed good composition of phenolics, flavonoids and terpenoids with outstanding antioxidant activities. The common secondary metabolites for organically produced P. quadrangularis in different plant parts include 2-isopropyl-3-methoxycinnamic acid (mesocarp and pulp), myricetin isomers (pulp and leaves), and malvidin-3-O-arabinoside isomers (pulp and leaves). This study confirmed that organic cultivated P. quadrangularis possessed higher antioxidant activities contributed by its vitamins and secondary metabolites.

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Section: Plos Onementioning

confidence: 98%

“…cyanogenic glycosides and harmine alkaloids were identified to be the major secondary metabolites in Passiflora leaves and possess bioactive properties [21,52,56]. The metabolites profiles have been reported varied with species, variants and cultivation system [38,57].…”

Section: Plos Onementioning

confidence: 99%

Organic cultivation practices enhanced antioxidant activities and secondary metabolites in giant granadilla (Passiflora quadrangularis L.)

et al. 2021

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“…The highest baicalin content was achieved at an extraction time of 60 min. Other works reported that extraction time also showed a positive impact on the flavonoid content of Passiflora quadrangularis leaves obtained using the percolation technique; total flavonoids content was increased when extraction time was increased from 24 to 72 h [33]. Uddin et al [34] optimized the extraction of polysaccharides from Pleurotus ostreatus.…”

Section: Resultsmentioning

confidence: 99%

Optimization of dynamic maceration of Clausena anisata (Willd.) Hook. f. ex Benth. leaves to maximize trans-anethole content

et al. 2021

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Trans-anethole possesses several biological and pharmacological effects. It is also used as masking agent in household products and as a flavoring agent in food. Clausena anisata (Willd.) Hook. f. ex Benth. leaves are reported as a source of trans-anethole that makes their anise-like odor. This work sought to optimize the dynamic maceration of C. anisata leaves to maximize the trans-anethole content. The circumscribed central composite experimental design was applied to investigate the effects of extraction temperature and time on extraction yield, trans-anethole content in the extract, and trans-anethole content in the plant raw material. The results showed that the extraction yield was high when C. anisata leaves were extracted over a long extraction time, while the extraction temperature had a lesser effect on the extraction yield. Trans-anethole content in the extract and plant raw material determined using a linear, specific, precise, and accurate HPLC method was high when a medium extraction temperature with a short extraction time was used. The optimal condition that maximized trans-anethole content involved an extraction temperature of 61.8 °C and an extraction time of 12.9 min, respectively. The percentage error of the prediction conducted by computer software was low, suggesting that the prediction was highly accurate. In conclusion, the optimal condition of dynamic maceration obtained from this work could be used as a guide for maximizing trans-anethole content from C. anisata leaves.

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“…Fernández‐Jalao et al () recorded a 30% of increase in TFC for Spain apples after HHP treatment (400 MPa, for 5 min). Echeverry et al () revealed a decrease in TFC in Passiflora quadrangularis leaf extracts by 28.2% under alkali hydrolysis and 7.8% under acid hydrolysis. A decrease (>54%) in total anthocyanin content was reported when been exposed to sunlight after 3 months (Bakowska et al , ).…”

Section: Introductionmentioning

confidence: 99%

Effects of processing and storage conditions on the stability of sweet potato (Ipomoea batatas L.) leaf flavonoids

Liu

Sun

et al. 2020

Int J of Food Sci Tech

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The effect of heat, high hydrostatic pressure (HHP) treatment, pH, light, temperature and simulated digestion on sweet potato leaf flavonoids (SPLF) stability was studied. Results showed heat treatment at 75°C for 90 min or HHP treatment at 600 MPa for 30 min did not cause significant effect on SPLF. Heat treatment at 100°C for 60 min and 90 min led to decrease in antioxidant activity by 20% and 25%, respectively, while pH 7.0 and 8.0 significantly decreased amount of SPLF by approximately 75%, decreased antioxidant activity by about 30% and 47% separately. Light treated samples recorded a decrease in SPLF by 52% and antioxidant activity by 24%. No significant effect on SPLF was observed for samples stored at À18°C, 4°C or room temperature. The retention of flavonoids and antioxidant activity was 45.9 AE 3.6% and 56.2 AE 2.6%, individually in SPLF after simulated digestion.Stability of sweet potato leaf flavonoids J. Liu et al.

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Optimization of flavonoid extraction from Passiflora quadrangularis leaves with sedative activity and evaluation of its stability under stress conditions

Cited by 19 publications

References 17 publications

Organic cultivation practices enhanced antioxidant activities and secondary metabolites in giant granadilla (Passiflora quadrangularis L.)

Organic cultivation practices enhanced antioxidant activities and secondary metabolites in giant granadilla (Passiflora quadrangularis L.)

Optimization of dynamic maceration of Clausena anisata (Willd.) Hook. f. ex Benth. leaves to maximize trans-anethole content

Effects of processing and storage conditions on the stability of sweet potato (Ipomoea batatas L.) leaf flavonoids

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