Optimization of hydrodistillation extraction using response surface methodology and Chemical composition of essential oil from Moroccan endemic medicinal plant Ballota hirsuta
Abstract:The present study describes for the first time the optimization of the extraction by hudrodistillation and chemical composition of the essential oil (EO) of Ballota hirsuta aerial parts using Gas chromatography (GC/FID) and GC-mass spectrometry (GC/MS) analysis. Single-factor experiments and response surface methodology (RSM) based on a central composite design (CCD) were used to optimize the EO extraction parameters including drying period (0–21 days), extraction time (60–240 min) and water/plant ratio (5–20 … Show more
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