Optimization of imaging parameters in chest CT for COVID-19 patients: an experimental phantom study

Niu, Yinong; Huang, Shibo; Zhang, Huan; Li, Shuo; Li, Xiaoting; Lv, Zhi; Yan, Shuo; Fan, Wei; Zhai, Yanlong; Wong, Eddy Y.; Wang, Kexin; Zongrui, Zhang; Chen, Budong; Xie, Ruming; Xian, Junfang

doi:10.21037/qims-20-603

Cited by 6 publications

(6 citation statements)

References 14 publications

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“…The routine chest CT protocol had been optimized in our radiology center to reduce the radiation dose of COVID-19 patients without reducing its efficiency. Several studies confirmed the effectiveness of low-dose and ultra-low-dose CT scans in detecting and evaluating COVID-19 [ 22 – 25 ]. Therefore, in pandemics such as COVID-19 where ionizing radiation is employed for screening or follow-up of a large population, radiation settings can be significantly lower than in routine scans [ 26 ].…”

Section: Discussionmentioning

confidence: 93%

COVID-19 and cancer risk arising from ionizing radiation exposure through CT scans: a cross-sectional study

Mahmoudi,

Toolee,

Maskani

et al. 2024

BMC Cancer

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Background The surge in the utilization of CT scans for COVID-19 diagnosis and monitoring during the pandemic is undeniable. This increase has brought to the forefront concerns about the potential long-term health consequences, especially radiation-induced cancer risk. This study aimed to quantify the potential cancer risk associated with CT scans performed for COVID-19 detection. Methods In this cross-sectional study data from a total of 561 patients, who were referred to the radiology center at Imam Hossein Hospital in Shahroud, was collected. CT scan reports were categorized into three groups based on the radiologist’s interpretation. The BEIR VII model was employed to estimate the risk of radiation-induced cancer. Results Among the 561 patients, 299 (53.3%) were males and the average age of the patients was 49.61 ± 18.73 years. Of the CT scans, 408 (72.7%) were reported as normal. The average age of patients with normal, abnormal, and potentially abnormal CT scans was 47.57 ± 19.06, 54.80 ± 16.70, and 58.14 ± 16.60 years, respectively (p-value < 0.001). The average effective dose was 1.89 ± 0.21 mSv, with 1.76 ± 0.11 mSv for males and 2.05 ± 0.29 mSv for females (p-value < 0.001). The average risk of lung cancer was 3.84 ± 1.19 and 9.73 ± 3.27 cases per 100,000 patients for males and females, respectively. The average LAR for all cancer types was 10.30 ± 6.03 cases per 100,000 patients. Conclusions This study highlights the critical issue of increased CT scan usage for COVID-19 diagnosis and the potential long-term consequences, especially the risk of cancer incidence. Healthcare policies should be prepared to address this potential rise in cancer incidence and the utilization of CT scans should be restricted to cases where laboratory tests are not readily available or when clinical symptoms are severe.

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Section: Discussionmentioning

confidence: 93%

COVID-19 and cancer risk arising from ionizing radiation exposure through CT scans: a cross-sectional study

Mahmoudi,

Toolee,

Maskani

et al. 2024

BMC Cancer

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“…An optimization study by Niu et al suggests kV = 100 and mAs = 40 for Covid-19 patient's chest CT scans ( Niu et al, 2021 ). In this study, different hospitals used different kV and mAs.…”

Section: Discussionmentioning

confidence: 99%

“…Regarding the pitch number, some studies suggest a pitch of less than 1 to have an image with enough quality to detect the ground-glass nodules ( Niu et al, 2021 ). However, other studies used pitch numbers of 1.4 and 1.5 and slice thickness of 5 mm, satisfying the results ( Samir et al, 2021a ; Song et al, 2020 ), similar to the results of H4 in this study.…”

Section: Discussionmentioning

confidence: 99%

Is it necessary to define new diagnostic reference levels during pandemics like the Covid19-?

Zeinali-Rafsanjani

Alavi

Lotfi

et al. 2023

Radiation Physics and Chemistry

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“…Dai et al (67) found that the image quality of the shelter hospital CT (CT Ark) had no obvious difference compared to ordinary CT (Brilliance 64) based on subjective observations. Andrea et al (68) and Niu et al (69) recognized that a low radiation dose could still provide sufficient diagnostic quality to exclude COVID-19. Bernardo et al (70) deemed that there was little difference in the distribution and lobar extent of pulmonary lesions on chest CT despite substantial differences in CT usage.…”

Section: Discussionmentioning

confidence: 99%

Do COVID-19 CT features vary between patients from within and outside mainland China? Findings from a meta-analysis

Hou

Wang

et al. 2022

Front. Public Health

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BackgroundChest computerized tomography (CT) plays an important role in detecting patients with suspected coronavirus disease 2019 (COVID-19), however, there are no systematic summaries on whether the chest CT findings of patients within mainland China are applicable to those found in patients outside.MethodsRelevant studies were retrieved comprehensively by searching PubMed, Embase, and Cochrane Library databases before 15 April 2022. Quality assessment of diagnostic accuracy studies (QUADAS) was used to evaluate the quality of the included studies, which were divided into two groups according to whether they were in mainland China or outside. Data on diagnostic performance, unilateral or bilateral lung involvement, and typical chest CT imaging appearances were extracted, and then, meta-analyses were performed with R software to compare the CT features of COVID-19 pneumonia between patients from within and outside mainland China.ResultsOf the 8,258 studies screened, 19 studies with 3,400 patients in mainland China and 14 studies with 554 outside mainland China were included. Overall, the risk of quality assessment and publication bias was low. The diagnostic value of chest CT is similar between patients from within and outside mainland China (93, 91%). The pooled incidence of unilateral lung involvement (15, 7%), the crazy-paving sign (31, 21%), mixed ground-glass opacities (GGO) and consolidations (51, 35%), air bronchogram (44, 25%), vascular engorgement (59, 33%), bronchial wall thickening (19, 12%), and septal thickening (39, 26%) in patients from mainland China were significantly higher than those from outside; however, the incidence rates of bilateral lung involvement (75, 84%), GGO (78, 87%), consolidations (45, 58%), nodules (12, 17%), and pleural effusion (9, 15%) were significantly lower.ConclusionConsidering that the chest CT features of patients in mainland China may not reflect those of the patients abroad, radiologists and clinicians should be familiar with various CT presentations suggestive of COVID-19 in different regions.

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Optimization of imaging parameters in chest CT for COVID-19 patients: an experimental phantom study

Cited by 6 publications

References 14 publications

COVID-19 and cancer risk arising from ionizing radiation exposure through CT scans: a cross-sectional study

COVID-19 and cancer risk arising from ionizing radiation exposure through CT scans: a cross-sectional study

Is it necessary to define new diagnostic reference levels during pandemics like the Covid19-?

Do COVID-19 CT features vary between patients from within and outside mainland China? Findings from a meta-analysis

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