Optimization of Lily Microbulb Scale Separation Operation

Hsieh, C. L.; Su, P. Y.; Chen, W. H.; Lin, Ta‐Te

doi:10.13031/2013.2681

Cited by 41 publications

(48 citation statements)

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“…SUN2, is an inner nuclear membrane protein with an evolutionarily conserved Sad1/UNC-84 homology (SUN) domain at the C-terminus of the protein (Turgay et al, 2010) and is a key component of the connection between the nuclear skeleton and cytoskeleton complex, highly conserved in all eukaryotes and widely expressed in various organs and tissues (Hsieh et al, 2014). SUN2 is also a novel anticancer drug candidate with the ability to inhibit the proliferation and migration of cancer cells and promote their apoptosis.…”

Section: Sad1/unc84 Domain-containing Protein 2 (Sun2)mentioning

confidence: 99%

Role and mechanism of DNA methylation and its inhibitors in hepatic fibrosis

et al. 2023

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Liver fibrosis is a repair response to injury caused by various chronic stimuli that continually act on the liver. Among them, the activation of hepatic stellate cells (HSCs) and their transformation into a myofibroblast phenotype is a key event leading to liver fibrosis, however the mechanism has not yet been elucidated. The molecular basis of HSC activation involves changes in the regulation of gene expression without changes in the genome sequence, namely, via epigenetic regulation. DNA methylation is a key focus of epigenetic research, as it affects the expression of fibrosis-related, metabolism-related, and tumor suppressor genes. Increasing studies have shown that DNA methylation is closely related to several physiological and pathological processes including HSC activation and liver fibrosis. This review aimed to discuss the mechanism of DNA methylation in the pathogenesis of liver fibrosis, explore DNA methylation inhibitors as potential therapies for liver fibrosis, and provide new insights on the prevention and clinical treatment of liver fibrosis.

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Section: Sad1/unc84 Domain-containing Protein 2 (Sun2)mentioning

confidence: 99%

Role and mechanism of DNA methylation and its inhibitors in hepatic fibrosis

et al. 2023

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“…Some reactions are known to adhere to these boundary conditions, including excited state intramolecular proton transfer (ESIPT), which is possibly the best-known example. 181,182 However, from a practical point of view, intermolecular PCeT in the excited state most often results in crossing to the ground state, i.e., quenching. Indeed, individual, sequential, or concerted electron and proton transfer (SeT, PT, and PCeT, respectively) compete with the formation of excited complexes (exciplexes) and electronic energy transfer (ET) induced deactivation of the donor excited state.…”

Section: Properties That Influence the Behavior Of Endogenous Photose...mentioning

confidence: 99%

Endogenous Photosensitizers in Human Skin

2023

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Endogenous photosensitizers play a critical role in both beneficial and harmful light-induced transformations in biological systems. Understanding their mode of action is essential for advancing fields such as photomedicine, photoredox catalysis, environmental science, and the development of sun care products. This review offers a comprehensive analysis of endogenous photosensitizers in human skin, investigating the connections between their electronic excitation and the subsequent activation or damage of organic biomolecules. We gather the physicochemical and photochemical properties of key endogenous photosensitizers and examine the relationships between their chemical reactivity, location within the skin, and the primary biochemical events following solar radiation exposure, along with their influence on skin physiology and pathology. An important take-home message of this review is that photosensitization allows visible light and UV-A radiation to have large effects on skin. The analysis presented here unveils potential causes for the continuous increase in global skin cancer cases and emphasizes the limitations of current sun protection approaches.

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“…Besides RT-PCR, several other diagnostic methods, most notably colorimetric-based rapid antigen tests (RATs), have emerged to complement COVID-19 testing. 60,129 RATs detect specic viral proteins, called antigens, in respiratory samples. The process of conducting a rapid antigen test involves collecting a respiratory sample, typically obtained through a nasal or throat swab.…”

Section: Infectious Disease Diagnosismentioning

confidence: 99%