Optimization of operation parameters in ultrafiltration process

Crossflow Filtraton: Literature Review

“…Suspension removal and ultrafiltration processes were both performed to optimize the operating conditions for ultrafiltration, specifically, the pumping rate (Liu and Wu, 1998). The suspension removal system used a cellulose acetate with a 0.2 μm pore rating as the filtering media while the ultrafilter used a hollow-fiber membrane of polysulphone with a filtration area of 775 in 2 .…”

Use of response surface methodology to optimise the hydrolysis of whey protein isolate in a tangential flow filter membrane reactor

“…However, although the TFF modules dramatically reduce the pressure impact compared to the tubular and hollow fibre modules, there is still bound to be some decay in the permeate flux. This is because it (permeate flux) is subject to many more variables than the transmembrane pressure such as substrate concentration, hence viscosity (Liu & Wu, 1998;Ramesh & Gaikar, 2001;Sirkar & Prasad, 1986). Studies of the effects of the operating conditions on permeate flux dynamics are, therefore, a necessity and are reviewed elsewhere (Cheison et al, 2006a).…”

“…Thus, J residual was influenced by the substrate concentration most prominently as given by the absolute magnitude of the positive regression coefficient. This is probably explained by the effect of substrate concentration/viscosity (Liu & Wu, 1998;Sirkar & Prasad, 1986) on the hydrodynamic flow as well as its contribution to the formation of gel layer (Porter, 1990).…”

“…The longer peptides are good for EMRs with higher NMWCO (Cheison et al, 2006a), to ensure that the shear forces are optimised in the peptide fragments in the UF interstices because of the erosional forces that entrain the peptide fragments. Permeate flux is influenced by a number of factors such as feed characteristics, hydrodynamic properties, transmembrane pressure and membrane geometry as well as process design and unit operations (Liu & Wu, 1998;Ramesh & Gaikar, 2001;Sirkar & Prasad, 1986). Enzymes are applied extensively in the detergents industry as well as in cleaning of membranes used in protein processing (Arguello, Alvarez, Riera, & Alvarez, 2002).…”

“…5a). This is explained by the constraining effect of the enzyme concentration in conversion of the product to sievable nitrogen due to substrate inhibition (Cheison et al, 2006a) as well as the likelihood of substrate viscosity impeding permeate flow dynamics (Liu & Wu, 1998;Ramesh & Gaikar, 2001). The interaction between the substrate and the enzyme, too, has a negative regression coefficient.…”