1991
DOI: 10.3109/03639049109057301
|View full text |Cite
|
Sign up to set email alerts
|

Optimization of Tablet Formulations Containing

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
5

Citation Types

0
8
0

Year Published

1992
1992
2016
2016

Publication Types

Select...
7
1

Relationship

0
8

Authors

Journals

citations
Cited by 27 publications
(8 citation statements)
references
References 22 publications
0
8
0
Order By: Relevance
“…This was described by Klein et al [7], and it was developed for controlled release of semen for artificial insemination in swine [8][9][10] and for 3D culture of ovarian follicular cells [11][12][13]. Recently, this technique has also been employed in 3D culture of other cell types: nucleus pulposus for regenerative therapy of intervertebral disc and adipose derived mesenchymal stem cells for in vitro expansion [14]. The barium alginate capsules are formed from a core containing the live cells surrounded by a gel membrane which may, if desired, be coated by an external layer of protamine-reacted alginate.…”
Section: Introductionmentioning
confidence: 98%
“…This was described by Klein et al [7], and it was developed for controlled release of semen for artificial insemination in swine [8][9][10] and for 3D culture of ovarian follicular cells [11][12][13]. Recently, this technique has also been employed in 3D culture of other cell types: nucleus pulposus for regenerative therapy of intervertebral disc and adipose derived mesenchymal stem cells for in vitro expansion [14]. The barium alginate capsules are formed from a core containing the live cells surrounded by a gel membrane which may, if desired, be coated by an external layer of protamine-reacted alginate.…”
Section: Introductionmentioning
confidence: 98%
“…Dawoodbhai et al [81] optimized the formulation of direct compression tablet products containing talc using SQP methodologies. The tablet dissolution and disintegration time in vitro was optimized from experimentally measurable manufacturing parameters such as friability, hardness, compression and ejection force.…”
Section: Product Formulationmentioning
confidence: 99%
“…All of these parameters were determined within feasible manufacturing values, which generated regions that served as the constraints for the SQP optimization. The characteristics and results of the optimized tablet formulation were analyzed by principal component analysis and described using response surface modeling [81].…”
Section: Product Formulationmentioning
confidence: 99%
“…The application of an optimization technique consisting of statistical design to pharmaceutical formulation development provides an efficient and economical method to acquire the necessary information to understand the relationship between controllable (independent) variables and performance dependent variables or responses (9). The technique of optimization is well reported in the literature for the development of tablet formulations (10)(11)(12).…”
Section: Introductionmentioning
confidence: 99%