In tropical climates, the main problems are high solar radiation and humidity. The aim of this study is to find the right insulation material to provide thermal comfort of BSPS houses in Pamekasan Regency. The method use in this study is experimental with quantitative data analysis. Experiments were conducted on aspects that affect the value of thermal transmittance (U-value) and type of materials (glass wool, VIPs, and aerogel). The result shows that the best insulation material for thermal comfort is Vacuum Insulation Panels (VIPs). It could provide a significant reduction in OTTV value. The final results of the research by applying the insulation system to the BSPS house of Pamekasan Regency, Proppo Subdistrict, Panaguan Village show that the OTTV value of the alternative model in a house type 24 m2 is 29.505-23.462 W/m2 with a decrease of 22.86%-38.66% while in a house type 33.12 m2 it is 30.205-24.217 W/m2 with a decrease of 22.74% -38.06% and in a house type 84.46 m2 it is 27.223-21.084 W/m2 with a decrease of 26.19%-42.84%. Furthermore, the best type and thickness of insulation material used in this study is Vacuum Insulation Panels (VIPs).