2024
DOI: 10.3389/fmicb.2024.1485624
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Optimizing Escherichia coli strains and fermentation processes for enhanced L-lysine production: a review

Zijuan Wu,
Tianpeng Chen,
Wenjun Sun
et al.

Abstract: lysine is an essential amino acid with significant importance, widely used in the food, feed, and pharmaceutical industries. To meet the increasing demand, microbial fermentation has emerged as an effective and sustainable method for L-lysine production. Escherichia coli has become one of the primary microorganisms for industrial L-lysine production due to its rapid growth, ease of genetic manipulation, and high production efficiency. This paper reviews the recent advances in E. coli strain engineering and fer… Show more

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