In pursuit of sustainable development and mitigation of the intermittency challenge associated with solar energy, this study proposes a hybrid solar system integrating waste heat incineration alongside solar power generation and distinct heat provision. Leveraging the superior energy efficiency of the organic Rankine cycle (ORC) in medium- and low-temperature scenarios, a parabolic trough collector (PTC) is selected for its cost-effectiveness and long-term operational reliability. Dowtherm A and toluene are identified as the optimal working fluids for the PTC and ORC, respectively. To optimize this complex system, a combination of artificial neural networks (ANNs) and multi-objective optimization via non-dominated sorting genetic algorithm II (NSGA-II) is employed, streamlining the optimization process. Thermal dynamic simulations are executed using Engineering Equation Solver (EES, V11) to validate the proposed system’s performance. TOPSIS is employed to identify the optimal solution from the Pareto frontier. The results indicate that the hourly cost of the system stands at USD 43.08, with an exergy efficiency of 22.98%. The economic analysis reveals that the solar collector constitutes the most significant portion of the total initial cost, representing 53.2%, followed by the turbine, thermoelectric generator (TEG), and waste heat incineration, in descending order of costliness.