Optimizing the Formulation of Poorly Water-Soluble Drugs

Ma, Xiangyu; Ellenberger, Daniel; O’Donnell, K. P.; Williams, Robert O.

doi:10.1007/978-3-030-88719-3_2

Cited by 2 publications

(1 citation statement)

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“…Poorly soluble drugs have different biopharmaceutical concerns such as less diffusion capacity, enough for intravenous intake, and adverse effects. The limitations of such drugs can be overcome by developing nano-materials in drug delivery systems 14 15 .…”

Section: Basics Of Nanotechnology Based Techniques In Designing Nanom...mentioning

confidence: 99%

Nanomedicines: A Focus on Nanomaterials as Drug Delivery System with Current Trends and Future Advancement

et al. 2022

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The rapid advancement of nanomedicine presents novel alternatives that have the potential to transform health care. Targeted drug delivery as well as the synthesis of nanocarriers is a growing discipline that has been intensively researched to reduce the complexity of present medicines in a variety of diseases and to develop new treatment and diagnostic techniques. There are several designed nanomaterials used as a delivery system such as liposomes, micelles, dendrimers, polymers, carbon-based materials, and many other substances, which deliver the drug moiety directly into its targeted body area reducing toxic effect of conventional drug delivery, thus reducing the amount of drug required for therapeutic efficacy and offering many more advantages. Currently, these are used in many applications, including cancer treatment, imaging contrast agents, and biomarker detection and so on. This review provides a comprehensive update in the field of targeted nano-based drug delivery systems, by conducting a thorough examination of the drug synthesis, types, targets, and application of nanomedicines in improving the therapeutic efficiency.

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Section: Basics Of Nanotechnology Based Techniques In Designing Nanom...mentioning

confidence: 99%