Optoacoustic imaging using a three-dimensional reconstruction algorithm

Köstli, Kornel P.; Frauchiger, D.; Niederhauser, J.J.; Paltauf, Guenther; Weber, H. P.; Frenz, Martin

doi:10.1109/2944.983294

Cited by 106 publications

(70 citation statements)

References 9 publications

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“…[14][15][16][17][18] In PAT, pulsed laser energy is delivered into biological tissue. The subsequent ultrasound signal generated by the photoacoustic ͑PA͒ effect is detected to form an image through a reconstruction algorithm.…”

Section: Introductionmentioning

confidence: 99%

Monkey brain cortex imaging by photoacoustic tomography

Yang

Wang

2008

J. Biomed. Opt.

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Abstract. Photoacoustic tomography ͑PAT͒ is applied to image the brain cortex of a monkey through the intact scalp and skull ex vivo. The reconstructed PAT image shows the major blood vessels on the monkey brain cortex. For comparison, the brain cortex is imaged without the scalp, and then imaged again without the scalp and skull. Ultrasound attenuation through the skull is also measured at various incidence angles. This study demonstrates that PAT of the brain cortex is capable of surviving the ultrasound signal attenuation and distortion caused by a relatively thick skull.

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Section: Introductionmentioning

confidence: 99%

Monkey brain cortex imaging by photoacoustic tomography

Yang

Wang

2008

J. Biomed. Opt.

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“…This description of the thermal diffusion is based on the Fourier's law, which is valid for macroscopic samples, where the propagation distance is much larger than the phonon mean free path. 29 The wave equation describes the acoustic pressure pðr; tÞ as a function of space r and time t and can be written as 30,31 …”

Section: Virtual Wave Signals Calculated From Local Temperature Smentioning

confidence: 99%

Three-dimensional thermographic imaging using a virtual wave concept

Burgholzer

Thor

Gruber

et al. 2017

Journal of Applied Physics

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In this work, it is shown that image reconstruction methods from ultrasonic imaging can be employed for thermographic signals. Before using these imaging methods, a virtual signal is calculated by applying a local transformation to the temperature evolution measured on a sample surface. The introduced transformation describes all the irreversibility of the heat diffusion process and can be used for every sample shape. To date, one-dimensional methods have been primarily used in thermographic imaging. The proposed two-stage algorithm enables reconstruction in two and three dimensions. The feasibility of this approach is demonstrated through simulations and experiments. For the latter, small steel beads embedded in an epoxy resin are imaged. The resolution limit is found to be proportional to the depth of the structures and to be inversely proportional to the logarithm of the signal-to-noise ratio. Limited-view artefacts can arise if the measurement is performed on a single planar detection surface. These artifacts can be reduced by measuring the thermographic signals from multiple planes, which is demonstrated by numerical simulations and by experiments performed on an epoxy cube.Comment: 22 pages, 8 figures, 1 appendix, acceapted by JA

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“…For instance, single Schlieren images can be applied to reconstruct pressure sources inside a sample, enabling real-time imaging of absorbing structures inside tissue [11]. Another approach is to measure the pressure dependent reflection of a collimated probe beam at the refractive index mismatch of the detection plane at different time delays [12]. The resulting 2D snapshot of the pressure distribution is then used to reconstruct a 3D image with a depth resolution of 15 microns and a lateral resolution of ∼ 100 microns.…”

Section: Introductionmentioning

confidence: 99%

Detection of laser induced dielectric breakdown in water using a laser doppler vibrometer

et al. 2010

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Abstract:This study is focused on exploring the feasibility of an all-optic surface scanning method in determining the size and position of a submerged, laser generated, optoacoustic (OA) source. The optoacoustic effect in this case was generated when the absorption of a short electromagnetic pulse in matter caused a dielectric breakdown, a plasma emission flash and a subsequent acoustic wave. In the experiment, a laser pulse with λ = 1064 nm and 12 ns pulse length was aimed at a volume of deionized water. When the laser beam was focused by a = 16 mm lens, a single dielectric breakdown spot occurred. When a = 40 mm was used several breakdowns in a row were induced. The breakdowns were photographed using a double shutter camera. The acoustic wave generated by the dielectric breakdowns were detected at a point on the water surface using a laser Doppler vibrometer (LDV). First, the LDV signal was used to calculate the speed of sound with an accuracy of 10 m/s. Secondly, the location and length of the dielectric breakdown was calculated with an accuracy of 1 mm. The calculated position matched the breakdown location recorded by a camera. The results show that it is possible to use LDV surface measurements from a single spot to determine both the position and length of the OA source as well as the speed of sound in the medium. Furthermore, the LDV measurements also show a secondary peak that originates from the OA source. To unravel the origin and properties of this interesting feature, further investigations are necessary.

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Optoacoustic imaging using a three-dimensional reconstruction algorithm

Cited by 106 publications

References 9 publications

Monkey brain cortex imaging by photoacoustic tomography

Monkey brain cortex imaging by photoacoustic tomography

Three-dimensional thermographic imaging using a virtual wave concept

Detection of laser induced dielectric breakdown in water using a laser doppler vibrometer

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