Oral and maxillofacial tuberculosis: A systematic review

Abstract

ObjectivesThis study aimed to analyze the demographic, clinical, histopathological, diagnosis, treatment, and follow‐up data on the occurrence of oral and maxillofacial tuberculosis (OMTB).MethodsElectronic searches without publication date restrictions were undertaken in four databases. Case reports and case series describing the occurrence of OMTB were included. Critical evaluation of studies was done using the Joanna Briggs Institute – University of Adelaide tool for case reports or case series.ResultsA total of 217 studies were included in the qualitative synthesis, for a total of 301 cases of OMTB. Of these patients, 192 (63.7%) were male, with an average age of 39.6 ± 19.8 (15 months to 81 years). The tongue (n = 80/26.6%) represented the most common affected site, followed by the mandible (n = 43/14.3%). The clinical presentation consisted mainly of a painful ulcerated lesion (n = 156/56.5%). Histopathological analysis showed a granulomatous inflammation in most cases (n = 156/63.1%). The main diagnostic methods used were sputum test (n = 53/26.8%), culture (n = 49/24.7%) and purified protein derivative (PPD), or Mantoux test (n = 49/24.7%). Antituberculosis therapy was used in 244 cases (100.0%) and 5.2% of patients died.ConclusionsThis systematic review provided clinical, demographic data and information about diagnostic methods of OMTB lesions and served as an important guide to assist health professionals in the early diagnosis of these lesions.

A case of oral tuberculous ulcer and literature review

“…case report summarizes the collected literatures related to oral tuberculosis and case details [13][14][15] (Table 1).…”

“…Tuberculosis pure protein derivative (PPD) test, chest imaging, immunology, bacteriology, and histopathology are helpful to the diagnosis. Pathological examination is the gold standard 5,13 . This case report summarizes the collected literatures related to oral tuberculosis and case details 13–15 (Table 1).…”

“…Pathological examination is the gold standard 5,13 . This case report summarizes the collected literatures related to oral tuberculosis and case details 13–15 (Table 1).…”

Orofacial Cryptococcosis: A Challenging Clinical Report and a Systematic Analysis of the Literature

“…Ultimately, in instances of single ulcerated lesions with indurated borders on the tongue, clinicians may hypothesize conditions such as histoplasmosis, tuberculosis, and oral squamous cell carcinoma. 52,59,60 The microscopic features of a cryptococcal lesion generally show a granulomatous inflammatory response to the organism. Cryptococcus spp.…”

“…Ultimately, in instances of single ulcerated lesions with indurated borders on the tongue, clinicians may hypothesize conditions such as histoplasmosis, tuberculosis, and oral squamous cell carcinoma. 52,59,60…”