Oral Azithromycin Pulse Therapy and Daily Topical Adapalene in the Treatment of Acne Vulgaris: An Open Randomized Noncomparative Study

Chowdhury, Mohammod Abu Hena; Mamun, Shameem Al; Uddin, Mohammad Jamal; Khan, Rahmat Ullah; Hoque, M Mujibul; Sikder, Akramullah

doi:10.3329/medtoday.v28i2.32925

Cited by 3 publications

(2 citation statements)

References 7 publications

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“…For the treatment of mild to moderate acne, the combination of benzoyl peroxide and topical retinoids is highly effective, addressing key pathophysiological elements such as abnormal keratinization and microbial colonization while reducing sebum production [3,[103][104][105][106][107][108][109][111][112][113][114][115][116]120,[122][123][124][125][126][130][131][132][133][134][135][136]138,146,[177][178][179][180][181][182][183]. Topical clindamycin in combination with benzoyl peroxide is recommended, leveraging the antimicrobial properties of clindamycin and the resistance-lowering effects of benzoyl peroxide, thereby enhancing therapeutic efficacy [126,135,[139][140][141][142][143][144].…”

Section: Mild To Moderate Acnementioning

confidence: 99%

Exploring Acne Treatments: From Pathophysiological Mechanisms to Emerging Therapies

Kim,

Kim

2024

IJMS

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Acne vulgaris is a common dermatological condition that can present across different ages but predominantly affects adolescents and young adults. Characterized by various lesion types, the pathogenesis of acne is complex, involving genetic, hormonal, microbial, and inflammatory factors. This review comprehensively addresses current and emerging acne management strategies, emphasizing both topical and systemic treatments, procedural therapies, and dietary modifications. Key topical agents include retinoids, benzoyl peroxide, antibiotics, and other specialized compounds. Systemic options like antibiotics, hormonal therapies, and retinoids offer significant therapeutic benefits, particularly for moderate to severe cases. Procedural treatments such as laser devices, photodynamic therapy, chemical peels, and intralesional injections present viable alternatives for reducing acne symptoms and scarring. Emerging therapies focus on novel biologics, bacteriophages, probiotics, and peptides, providing promising future options. This review underscores the importance of personalized approaches to treatment due to the multifaceted nature of acne, highlighting the potential of innovative therapies for improving patient outcomes.

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Section: Mild To Moderate Acnementioning

confidence: 99%

Exploring Acne Treatments: From Pathophysiological Mechanisms to Emerging Therapies

Kim,

Kim

2024

IJMS

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“… Adapalene : Primarily used topical retinoid drug for treating mild-moderate acne patients. It has more advantages than other retinoids like Tretinoin and Tazarotene and is considered a first-line therapy for acne treatment [ 40 ]. It helps to reduce the hyperkeratinization of pilosebaceous follicles, inflammation caused by acne.…”

Section: Conventional Medications For Acne Treatmentmentioning

confidence: 99%

Acne vulgaris: A review of the pathophysiology, treatment, and recent nanotechnology based advances

Vasam,

Korutla,

Bohara

2023

Biochemistry and Biophysics Reports

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The role of current synthetic and possible plant and marine phytochemical compounds in the treatment of acne

Ramsis,

Refat M. Selim,

Elseedy

et al. 2024

RSC Adv.

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Oral Azithromycin Pulse Therapy and Daily Topical Adapalene in the Treatment of Acne Vulgaris: An Open Randomized Noncomparative Study

Abstract: The

Cited by 3 publications

References 7 publications

Exploring Acne Treatments: From Pathophysiological Mechanisms to Emerging Therapies

Exploring Acne Treatments: From Pathophysiological Mechanisms to Emerging Therapies

Acne vulgaris: A review of the pathophysiology, treatment, and recent nanotechnology based advances

The role of current synthetic and possible plant and marine phytochemical compounds in the treatment of acne

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