Oral Lichen Planus: A Review of Etiopathogenesis, Clinical, Histological and Treatment Aspects

Chitturi, Ravi Teja

doi:10.4172/2376-032x.1000142

Cited by 16 publications

(26 citation statements)

References 28 publications

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“…In addition most literature sources point erosive and atrophic forms as carrying the highest malignant risk. 3,4,23 In the present study six patients with erosive form, five patients with atrophic form and one patient with bullous-erosive form were included. According to the results obtained in this study, a downward shift of the VAS score after LLLT occurred in all of the patients.…”

Section: Discussionmentioning

confidence: 99%

“…Andreasen's classification distinguishes six clinical forms of OLP: reticular, papular, plaque-like, atrophic (erythematous), erosive-ulcerous and bullous-erosive. [3][4][5][6][7] Reticular, papular and plaque-like forms are usually painless and present clinically as white keratotic lesions. The other non-keratotic forms are associated with severe pain and intolerance of patients to consume hot or spicy food.…”

mentioning

confidence: 99%

“…Furthermore, the risk of malignant transformation in erosive and atrophic lesions may be higher than other types of OLP. 3,4,8 Therefore, treatment of this forms and monitoring in the long term are vital.…”

mentioning

confidence: 99%

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Effects of Low Level Laser Therapy on Erosive-atrophic Oral Lichen Planus

Mutafchieva¹,

Draganova-Filipova²,

Zagorchev³

et al. 2018

Folia Medica

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Background: The erosive-atrophic form of oral lichen planus (OLP) is associated with severe pain and burning sensation and is often unresponsive to treatment. Topical corticosteroids are considered as a medication of first choice but they can produce adverse effects. Therefore, new therapeutic approaches are required. Aim: The aim of this study was to investigate the effectiveness of biomodulation with diode laser in patients presenting with long-standing erosive-atrophic OLP. Materials and methods: Twelve patients, clinically and histologically diagnosed with OLP, participated in this study. The level of pain and the clinical scores of total 59 lesions were recorded before treatment using visual analog scale and Thongprasom sign scoring system respectively. All patients received low level laser therapy (LLLT) with diode laser (810 nm) with parameters (0.5 W, 30 s, 1.2 J/cm2) three times weekly for a month. The response rate was assessed according to the decrease in pain and sign scores. Treatment efficacy index was calculated. Results: There was a significant reduction in pain after LLLT (p<0.0001). Improvement in clinical signs was achieved in 59.3% of the lesions. At the end of the treatment 5.1% of the lesions exhibited score 5; 6.8% - score 4, 11.9% of the lesions were scored 3 and 8.5% and 30.5% showed score 2 and score 1, respectively. Complete resolution was revealed in 37.3% of the lesions. All patients experienced some degree of improvement. Most of the cases showed moderate recovery. Conclusion: The present results indicate that LLLT is an effective and harmless modality for management of erosive-atrophic OLP.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

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Effects of Low Level Laser Therapy on Erosive-atrophic Oral Lichen Planus

Mutafchieva¹,

Draganova-Filipova²,

Zagorchev³

et al. 2018

Folia Medica

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“…may have an increased potential for malignant transformation into OSCC. [6][7][8][9] These lesions are the precursor lesions for OSCC and diagnosis of these disorders are of prime importance to prevent malignant transformation as these can be reverted back if intervened correctly. The 5 years survival rate of patients with OSCC is found to be significantly improved when diagnosed early.…”

Section: Introductionmentioning

confidence: 99%

The role of exfoliative cytology and molecular biology in oral potentially malignant disorders

et al. 2017

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According to the latest statistics, oral squamous cell carcinoma is the 9 th most common cancer to diagnose worldwide, especially in males and in the developing countries and cause for high mortality and morbidity. Oral potentially malignant disorders (OPMD's) are an important entity associated as precusors for most of these cases which are reversible. Hence, early detection of OPMD's can be very useful. Exfoliative cytology is a practically very easy and patient-friendly method to collect cells from these lesions. They can be subjected to a variety of analysis to help us detect oral cancer in advance. This review describes all the techniques have been used in early detection right from the conventional techniques to molecular diagnostics.

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“…Erosiver oraler Lichen planus (EOLP), die zweithäufigste Form, geht oft mit erheblichen Schmerzen und Unbehagen für den Patienten einher und beeinträchtigt dadurch ihre Lebensqualität. Erosiver oraler Lichen planus hat ein erhebliches Potential zur malignen Transformation; das Risiko wird zwischen 0,5–2 % angesiedelt .…”

Section: Introductionunclassified