Oral Sulfate Solution is as Effective as 2 L Polyethylene Glycol Plus Ascorbic Acid

Shin, Sung Hyun; Kwon, Kwang An

doi:10.5946/ce.2020.227

Cited by 2 publications

(1 citation statement)

References 10 publications

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“… 9 All patients should be educated on the split-dosing regimen for bowel preparation. Recently, low-volume preparation agents have been commonly used 42 , 43 ; therefore, sufficient education on low-fiber diets is becoming more important than before, when high-volume preparation agents were commonly used. European guidelines recommend a low-fiber diet on the day before colonoscopy but do not have any recommendations about the use of a low-fiber diet for >24 hours before the procedure.…”

Section: Bowel Preparation Adequacymentioning

confidence: 99%

Quality indicators in colonoscopy: the chasm between ideal and reality

Park

Myung

2022

Clin Endosc

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Continuous measurement of quality indicators (QIs) should be a routine part of colonoscopy, as a wide variation still exists in the performance and quality levels of colonoscopy in Korea. Among the many QIs of colonoscopy, the adenoma detection rate, average withdrawal time, bowel preparation adequacy, and cecal intubation rate should be monitored in daily clinical practice to improve the quality of the procedure. The adenoma detection rate is the best indicator of the quality of colonoscopy; however, it has many limitations for universal use in daily practice. With the development of natural language processing, the adenoma detection rate is expected to become more effective and useful. It is important that colonoscopists do not strictly and mechanically maintain an average withdrawal time of 6 minutes but instead perform careful colonoscopy to maximally expose the colonic mucosa with a withdrawal time of at least 6 minutes. To achieve adequate bowel preparation, documentation of bowel preparation with the Boston Bowel Preparation Scale (BBPS) should be a routine part of colonoscopy. When colonoscopists routinely followed the bowel preparation protocols, ≥85% of outpatient screening colonoscopies had a BBPS score of ≥6. In addition, the cecal intubation rate should be ≥95% of all screening colonoscopies. The first step in improving colonoscopy quality in Korea is to apply these key performance measurements in clinical practice.

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Section: Bowel Preparation Adequacymentioning

confidence: 99%

Quality indicators in colonoscopy: the chasm between ideal and reality

Park

Myung

2022

Clin Endosc

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Efficacy, safety and tolerability of oral sulphate tablet for bowel preparation in patients with inflammatory bowel disease: A multicentre randomized controlled study

Kim¹,

Kim

Lee

et al. 2022

Journal of Crohn's and Colitis

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Background and Aims We evaluated the efficacy, safety and tolerability of novel oral sulphate tablets [OSTs] vs 2 L of polyethylene glycol and ascorbate [PEG/Asc] in patients with inflammatory bowel disease [IBD]. Patients and Methods A total of 110 patients with clinically inactive IBD were enrolled in this single-blind multicentre non-inferiority study. Patients were randomly assigned to the OST or 2 L PEG/Asc group and we applied a split-dose regimen. The primary efficacy endpoint was bowel cleansing success rate defined as Harefield Cleansing Scale Grade A or B. The secondary endpoints were perfect preparation rate, the presence of air bubbles, safety as assessed by laboratory abnormalities and self-reported adverse events, or IBD symptom flare-ups. Tolerability was assessed by a pre-procedural visual analog scale [VAS] interview. Results Both groups showed high cleansing success rates [98.1%] and there was no significant difference in perfect preparation rate. The proportion of a bubble score 0 was significantly higher in the OST group [94.5% vs 50.0%, p < 0.001]. There was no significant intergroup difference in vomiting or bloating. Symptom flare-ups occurred in two OST group patients. No clinically significant blood test abnormalities were noted in either group. Ease of ingestion and taste scores were significantly higher in the OST group. More patients in the OST group [94.5%] wanted to take the same preparation agent for their next colonoscopy. Conclusions Both OST and 2 L PEG/Asc demonstrated high successful cleansing and safety in patients with inactive IBD. OST achieved higher satisfaction than 2 L PEG/Asc. Our results suggest that the OST split-dose regimen is effective and safe for patients with inactive IBD.

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Oral Sulfate Solution is as Effective as 2 L Polyethylene Glycol Plus Ascorbic Acid

Cited by 2 publications

References 10 publications

Quality indicators in colonoscopy: the chasm between ideal and reality

Quality indicators in colonoscopy: the chasm between ideal and reality

Efficacy, safety and tolerability of oral sulphate tablet for bowel preparation in patients with inflammatory bowel disease: A multicentre randomized controlled study

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