Orbital myositis as an initial manifestation of Behcet's disease

Abe, Shinya; Yunoki, Tatsuya; Hayashi, Atsushi

doi:10.1016/j.ajoc.2022.101630

Cited by 3 publications

(3 citation statements)

References 26 publications

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“…7 There are few associations between orbital myositis and Behçet's disease, as mentioned in Table 1. 7,8,11,[12][13][14] It is rarely reported as an initial manifestation of Behçet's disease, as illustrated in our case. 7,13,14 To the best of our knowledge, this is the fourth reported case of Behçet's disease caused by an inflammatory orbital pseudotumor.…”

Section: Discussionmentioning

confidence: 59%

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Case Report: Inflammatory orbital pseudotumor revealing Behçet's disease: an original observation

Sayhi,

Yahyaoui,

Dhahri

et al. 2024

F1000Res

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Objective To provide an original observation of Behçet’s disease, revealed by an inflammatory pseudotumor of the orbit. Methods We reported an observation of an inflammatory pseudotumor of the orbit that revealed Behçet’s disease. Results Twenty-Eight years old patient was admitted to the internal medicine department for painful edema in the right eye with headache and loss of visual acuity. Ophthalmologic examination revealed eye protrusion with conjunctival hyperemia. Orbital MRI resonance imaging revealed periorbital inflammatory thickening associated with inflammatory myositis. Behçet’s was diagnosed based on a history of recurrent oral aphthous since childhood, pseudofolliculitis, pathergy test positivity, and negativity of the rest of the etiological investigations. The evolution was spectacular with boli methylprednisolone and colchicine prescriptions. Conclusion Although the association is rare, Behçet’s disease should be included in the workup of inflammatory pseudotumors of the orbit.

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Section: Discussionmentioning

confidence: 59%

“…6 Other locations have been described: the heart, 9 brain, 10 and orbit. [11][12][13] Myositis associated with Behçet's disease is rare. It mainly affects the skeletal muscles.…”

Section: Discussionmentioning

confidence: 99%

Case Report: Inflammatory orbital pseudotumor revealing Behçet's disease: an original observation

Sayhi,

Yahyaoui,

Dhahri

et al. 2024

F1000Res

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“…In fact, TED is the most commonly associated disease with NSOI. Other conditions linked to NSOI are Crohn's disease [10][11][12], psoriasis [13], discoid lupus [14][15][16], Behçet disease [17,18], sarcoidosis [19], Wegener's granulomatosis [20], Churg-Strauss syndrome [21,22], and giant cell arthritis [23][24][25]. It is important to remember that NSOI may present with other connective tissue diseases, and it should always remain on the list of differentials until another cause can be identified.…”

Section: Etiologies Of Nonspecific Orbital Inflammationmentioning

confidence: 99%

Nonspecific Orbital Inflammation (NSOI): Unraveling the Molecular Pathogenesis, Diagnostic Modalities, and Therapeutic Interventions

Wu,

Kulbay,

Daigle

et al. 2024

IJMS

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Nonspecific orbital inflammation (NSOI), colloquially known as orbital pseudotumor, sometimes presents a diagnostic and therapeutic challenge in ophthalmology. This review aims to dissect NSOI through a molecular lens, offering a comprehensive overview of its pathogenesis, clinical presentation, diagnostic methods, and management strategies. The article delves into the underpinnings of NSOI, examining immunological and environmental factors alongside intricate molecular mechanisms involving signaling pathways, cytokines, and mediators. Special emphasis is placed on emerging molecular discoveries and approaches, highlighting the significance of understanding molecular mechanisms in NSOI for the development of novel diagnostic and therapeutic tools. Various diagnostic modalities are scrutinized for their utility and limitations. Therapeutic interventions encompass medical treatments with corticosteroids and immunomodulatory agents, all discussed in light of current molecular understanding. More importantly, this review offers a novel molecular perspective on NSOI, dissecting its pathogenesis and management with an emphasis on the latest molecular discoveries. It introduces an integrated approach combining advanced molecular diagnostics with current clinical assessments and explores emerging targeted therapies. By synthesizing these facets, the review aims to inform clinicians and researchers alike, paving the way for molecularly informed, precision-based strategies for managing NSOI.

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Multiple drugs

2022

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Orbital myositis as an initial manifestation of Behcet's disease

Cited by 3 publications

References 26 publications

Case Report: Inflammatory orbital pseudotumor revealing Behçet's disease: an original observation

Case Report: Inflammatory orbital pseudotumor revealing Behçet's disease: an original observation

Nonspecific Orbital Inflammation (NSOI): Unraveling the Molecular Pathogenesis, Diagnostic Modalities, and Therapeutic Interventions

Multiple drugs

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