Orbital Rhabdomyosarcoma

Abstract

Survival of orbital RMS has improved due to advances in chemotherapy and radiotherapy. Posttreatment complications, including side effects of radiotherapy and secondary orbital malignancies, as well as visual dysfunction, occur more often and present new challenges due to improved long-term survival.

Pediatric Orbit Tumors and Tumorlike Lesions: Nonosseous Lesions of the Extraocular Orbit

“…CT is particularly suited for showing bone involvement (Figs 2, 3c), and MR imaging is sensitive for depicting intracranial extension (Fig 3). Serial follow-up CT may show healing or worsening of bone involvement, indicating the degree of response to treatment, and residual or recurrent disease may be observed with MR imaging (8,14). A worse prognosis is associated with residual disease after treatment.…”

Embryonal rhabdomyosarcoma of the caruncle in a 4 year-old boy: case report

“…In adolescent or adult patients (not in infants where growth bone disturbances can occur) external beam radiotherapy can be combined with chemothe- rapy. Some authors (1) , due to the post-radiation complications, pro pose to use radiotherapy only in cases with bad response to che motherapy (1) . There is an innovative therapeutic approach for a rhabdomyosarcoma with brachytherapy with strontium-904, whose adva ntage is the high surface dose combined with a minimal depth of irradiation.…”

“…Even thought, it is the most common soft tissue sarcoma in childhood, with a mean age of 6 to 8 years at diagnosis (1) . It can occur in any anatomic location of the body where there is skeletal muscle, as well as other sites without skeletal muscle, such as the soft tissues of the orbit.…”

“…Rhabdomyosarcoma is a rare tumor, with an annual incidence of 4.3 cases per million children (1) . Even thought, it is the most common soft tissue sarcoma in childhood, with a mean age of 6 to 8 years at diagnosis (1) .…”

Childhood orbital rhabdomyosarcoma: Report from Children’s Cancer Hospital-57357-Egypt

“…Survival of orbital RMS has improved due to advances in chemotherapy and radiotherapy. Post treatment complications, including side effects of radiotherapy and secondary orbital malignancies, as well as visual dysfunction, occur more often and present new challenges due to improved long-term survival [6] .…”