Organic selenium supplementation improves growth parameters, immune and antioxidant status of newly received beef cattle

Rossi, C.A. Sgoifo; Compiani, R.; Baldi, G.; Muraro, Maria Antonella; Marden, Jean-Philippe; Rossi, Raffaella; Pastorelli, G.; Corino, C.; Dell’Orto, V.

doi:10.22358/jafs/70765/2017

Cited by 23 publications

(31 citation statements)

References 31 publications

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“…These findings agree with those reported by Ran, who posited that supplementation of the diet with selenium-enriched yeast appeared to be more effective than supplementation with sodium selenite [34]. Similar results were obtained by Gunter et al [32] and Rossi et al [35] who noted that supplementation with selenium-enriched yeast https://doi.org/10.1371/journal.pone.0233456.g004…”

Section: Plos Onesupporting

confidence: 91%

Preliminary study on Se-enriched Lentinula edodes mycelium as a proposal of new feed additive in selenium deficiency

et al. 2020

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The presence of selenium in European soil is low and this causes its deficiency in livestock and, in consequence, in humans. This study aimed to obtain Lentinula (L.) edodes mycelium with the maximum content of selenium. This species was used for experiment based on its documented medicinal properties. Calves were fed with selenium-enriched L. edodes mycelium, and serum selenium concentration, average daily weight gains and selected immune parameters were estimated. The selenium-enriched mushroom was found to be safe based on cytotoxicity tests (MTT and LDH tests) and for this reason it was used for further experiments. The mean quantity of selenium in the serum of calves fed with selenium-enriched L. edodes mycelium was significantly higher than that of control calves. Additionally, the calves fed with selenium-enriched L. edodes mycelium had higher body weight gains than those of control calves. White blood cell counts and subpopulations of lymphocytes in the experimental and control calves were within the reference range. The administration of L. edodes enriched with selenium had a beneficial effect on state of health of the calves.

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Section: Plos Onesupporting

confidence: 91%

Preliminary study on Se-enriched Lentinula edodes mycelium as a proposal of new feed additive in selenium deficiency

et al. 2020

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“…Similar to our results, the addition of a pro-oxidant to PBMCs from 13-month-old calves vaccinated against BHV-1 resulted in reduced cell antioxidant capacity and lower concentration of neutralizing antibodies against BHV-1 [57]. These results from animals with a mature immune system are comparable with our findings from calves with a naïve immune system.…”

Section: Antigen-specific Antibody Productionsupporting

confidence: 91%

Oxidative Stress Compromises Lymphocyte Function in Neonatal Dairy Calves

2021

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Dairy calves are unable to mount an effective immune response during their first weeks of life, which contributes to increased disease susceptibility during this period. Oxidative stress (OS) diminishes the immune cell capabilities of humans and adult cows, and dairy calves also experience OS during their first month of life. However, the impact that OS may have on neonatal calf immunity remains unexplored. Thus, we aimed to evaluate the impact of OS on newborn calf lymphocyte functions. For this, we conducted two experiments. First, we assessed the association of OS status throughout the first month of age and the circulating concentrations of the cytokines interferon-gamma (IFN-γ) and interleukin (IL) 4, as well as the expression of cytokine-encoding genes IFNG, IL2, IL4, and IL10 in peripheral mononuclear blood cells (PBMCs) of 12 calves. Subsequently, we isolated PBMCs from another 6 neonatal calves to investigate in vitro the effect of OS on immune responses in terms of activation of lymphocytes, cytokine expression, and antibody production following stimulation with phorbol 12-myristate 13-acetate or bovine herpesvirus-1. The results were compared statistically through mixed models. Calves exposed to high OS status in their first month of age showed higher concentrations of IL-4 and expression of IL4 and IL10 and lower concentrations of IFN-γ and expression of IFNG and IL2 than calves exposed to lower OS. In vitro, OS reduced lymphocyte activation, production of antibodies, and protein and gene expression of key cytokines. Collectively, our results demonstrate that OS can compromise some immune responses of newborn calves. Hence, further studies are needed to explore the mechanisms of how OS affects the different lymphocyte subsets and the potential of ameliorating OS in newborn calves as a strategy to augment the functional capacity of calf immune cells, as well as enhance calves’ resistance to infections.

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“…In fact, it is well known that the benefits of Se, and in particular of organic Se (namely SeMet), deposited in the tissue of animals appear when the animals face specific stressful physiological, environmental, nutritional and/or technological situations [ 12 , 40 ]. Sgoifo Rossi et al [ 41 ] have shown a growth performance improvement in beef cattle supplemented with organic Se, compared to inorganic Se, but after a long-lasting Se supplementation and on younger animals, and this might be explained by the higher bioavailability of organic Se having a positive effect on the health and antioxidant status. Silva et al [ 24 ], comparing SS and SY in an 84-day supplementation study, reported an increased dressing percentage for SY-fed cattle, but when using a much higher Se supplementation level (0.3, 0.9, 2.7 mg Se/kg DM) than those used in the present trial (0.2 mg Se/kg DM).…”

Section: Discussionmentioning

confidence: 99%

The Effect of Different Sources of Selenium Supplementation on the Meat Quality Traits of Young Charolaise Bulls during the Finishing Phase

Grossi

Rossi

Marco³

et al. 2021

Antioxidants

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The aim of the study was to compare the effects of sodium selenite (SS), selenium yeast (SY), and hydroxy-selenomethionine (OH-SeMet) on the meat quality and selenium (Se) deposition of finishing beef cattle. Sixty-three bulls were distributed over 3 treatments and fed SS, SY, or OH-SeMet at 0.2 mg kg−1 dry matter (DM) for 60 d. None of the Se sources affected the growth performance or carcass characteristics. OH-SeMet showed a higher Se transfer to the meat than SS or SY (p < 0.01). SY and OH-SeMet reduced the shear force of the meat (p < 0.0001), improved pH (p < 0.001), and reduced the drip losses (p < 0.001) and the lipid oxidation of the meat (p < 0.001). During 8 d of storage, OH-SeMet showed higher levels of meat lightness (L*) and yellowness (b*) than SS (p < 0.001), while the SY meat showed a higher L* than SS, albeit only on d 6. OH-SeMet improved b*, compared to SS, and also compared to SY on days 4, 7, and 8 (p < 0.001). Supplementing beef with SY and OH-SeMet improved several meat quality parameters. OH-SeMet appears to be the most effective strategy to improve the Se content and color stability of beef cattle meat.

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Organic selenium supplementation improves growth parameters, immune and antioxidant status of newly received beef cattle

Cited by 23 publications

References 31 publications

Preliminary study on Se-enriched Lentinula edodes mycelium as a proposal of new feed additive in selenium deficiency

Preliminary study on Se-enriched Lentinula edodes mycelium as a proposal of new feed additive in selenium deficiency

Oxidative Stress Compromises Lymphocyte Function in Neonatal Dairy Calves

The Effect of Different Sources of Selenium Supplementation on the Meat Quality Traits of Young Charolaise Bulls during the Finishing Phase

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