Organic small-molecule fluorescent probe-based detection for alkali and alkaline earth metal ions in biological systems

Abstract

The review describes the progress of research on the detection of alkali and alkali earth metals by organic small molecule fluorescent probes in terms of metal ion recognition groups.

Deciphering biomolecular complexities: the indispensable role of surface-enhanced Raman spectroscopy in modern bioanalytical research

“…68 Their functions are multifarious, ranging from serving as enzyme cofactors to aiding in the stabilization of intricate protein topologies. 69 These metal ions often associate with a spectrum of 67 biological macromolecules or smaller molecular entities, forming a gamut of complexes that are then poised for specific biological actions. 70 SERS has burgeoned as a seminal tool in the analytical armamentarium for discerning metal ions and their associated conjugates.…”

A novel isophorone-based fluorescent probe for recognizing Al3+ and its bioimaging in plants

“…In recent years, many fluorescent sensors have been developed and applied to the detection of metal ions. 16–19 Compared with traditional detection methods, 20 fluorescence detection techniques have the advantages of fast response speed, 21,22 simple operation, 23 low detection limit, 24 high specificity, 25 and portability. 23 However, some fluorescence detection techniques still have some limitations, 15 including emission in the visible region, short emission wavelength, small Stokes shift, long response time, single emission, and overlap of emission and excitation wavelengths.…”

A new two-dimensional, spiropyran-based polymer fluorescent nanoprobe with quantitative-fluorescent and photochromic properties for multi-substance detection

“…To improve the detection ability on the contaminants, an emerging technology based on fluorescent probes, with high selectivity and low operating cost, has been established in recent years [7]. For example, it can be promisingly applied for the detection of the metal-ion during environmental monitoring [8][9][10], food inspection [11] and biological imaging [12,13]. The working principle of a fluorescent probe on the detection of ions often lies in the probe-ion interaction that generates a characteristic fluorescent spectrum under light excitation [14].…”