Original Articles Preoperative Hematological Parameters for Predicting Ovarian Torsion in Patients with Mature Cystic Teratoma

Abstract

Objective The objective of this study is to evaluate the preoperative hematological parameters to predict ovarian torsion in patients with ovarian mature cystic teratoma. We also analyzed the diagnostic value of these makers to predict ovarian necrosis in cases of torsion as well as the effect of torsion on ovarian reserve. Patients and Methods This is a retrospective study of 132 patients who received either laparoscopic or laparotomy surgery for OMCT at a single university hospital. Clinical characteristics and preoperative hematological parameters were compared between patients with or without torsion. Patients with torsion were further classified as infarction and non-infarction group. Preoperative parameters were compared between the two groups as well. Results White blood cell (WBC) count, neutrophil percent, neutrophil count, and neutrophil to lymphocyte ratio (NLR) were higher in the torsion group (n=37) than the non-torsion group (n=95) ( p <0.05 for all). Although statistically insignificant, the preoperative anti-Mullerian hormone (AMH) was lower in the torsion group than the non-torsion group (4.07 ± 3.38 vs 6.1 ± 3.6, p =0.122). In cases of torsion, the infarction group showed higher WBC count and lymphocyte count but lower hemoglobin level and platelet to lymphocyte ratio (PLR) than the non-infarction group ( p <0.05 for all). Conclusion The WBC count, neutrophil percent, neutrophil count, and NLR were higher in the cases of OMCT with torsion, and these parameters may be useful to diagnose OMCT with torsion. Also, adnexal torsion may deteriorate ovarian reserved as indicated by decreased AMH in torsion group.

Predictive Role of Neutrophil to Lymphocyte Ratio in Adnexal Torsion: A Systematic Review and Meta-Analysis

“…In total, 15 articles were included in the analysis [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15], including 1156 patients with AT and 1460 patients with other adnexal masses. All of them were retrospective [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15]. One study was written in Turkish [4] and 14 in English [1,2,3,[5][6][7][8][9][10][11][12][13][14][15].…”

“…All of them were retrospective [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15]. One study was written in Turkish [4] and 14 in English [1,2,3,[5][6][7][8][9][10][11][12][13][14][15]. One of them was conference paper [8], and 14 were journal papers [1][2][3][4][5][6][7][9][10][11][12][13][14][15].…”

“…One study was written in Turkish [4] and 14 in English [1,2,3,[5][6][7][8][9][10][11][12][13][14][15]. One of them was conference paper [8], and 14 were journal papers [1][2][3][4][5][6][7][9][10][11][12][13][14][15]. Ten studies were conducted in Turkey [1-5, 10-13, 15], three in Korea [6][7][8], one in Israel [9], and one in China [14].…”

“…The nonspecific symptoms of AT, such as vomiting, nausea, and low-grade fever, often complicates its diagnosis. As studies continue to emerge on the utility of NLR in AT [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15], the need for a systematic review to guide clinical decision-making is essential. The key is to understand what an elevated ratio might mean for a patient with possible AT, to institute early interventions and improve outcomes.…”

Tuboovaryan apseli hastalarda sistemik inflamatuvar belirteçlerin medikal tedavi başarısızlığını öngörmedeki yeri

“…Ancak yine de hangi hastaların cerrahi tedavi gereksinimi olacağı net bilinmemektedir (5,6). Nötrofil lenfosit oranı (NLR), Platelet lenfosit oranı (PLR) son yıllarda bazı hastalıkların takip ve tanısında kullanılabilen sistemik inflamatuar belirteçlerdir (7)(8)(9). Aspartate aminotransferaz / Platelet (APRİ) Index skoru kolayca hesaplanabilen, karaciğerdeki inflamasyonun şiddetini göstermek için tanımlanmış olsa da birçok inflamatuar süreci öngörmede bir belirteç olarak kullanılabileceği gösterilmiştir (10)(11)(12).…”