“…Although H + -producing and consuming steps are seen, no autocatalysis pathway has been identified so far. [45][46][47][48] Towards higher complexity in inorganic networks, multifeedback pH-oscillation systems, oscillation amplification, oscillation elimination, 49 beat phenomenon, 50 and synchronization 51 were achieved successfully in recent years. Subsequently, moving towards organic CRNs, Taylor and co-workers introduced the first experimental example of an organic-based pH-oscillator utilizing the base-catalysed dehydration of methylene glycol as a source of positive feedback (OH À autocatalysis) This journal is © The Royal Society of Chemistry 2023 coupled with the base-catalysed hydrolysis of gluconic acid d-lactone (d-GL) for negative feedback (H + production).…”