Osteochondritis Dissecans

Hefti, Fritz; Beguiristáin, J. L.; Krauspe, R.; Möller‐Madsen, Bjarne; Riccio, Vincenzo; Tschauner, Christian; Wetzel, Reinhard; Zeller, Reinhard

doi:10.1097/01202412-199910000-00001

Cited by 50 publications

(92 citation statements)

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“…Consequently, we did not observe inflammation, seroma formation, or other major complications in our study cohort. This was also true in prior comparable studies 4 , 9 .…”

Section: Discussionsupporting

confidence: 79%

“…Further, the required drilling prior to the pinʼs insertion may favor vessel ingrowth into the devitalized fragment and stimulate healing 28 . Moreover, they do not provoke the observation of artifacts on postoperative MRI scans 4 .…”

Section: Discussionmentioning

confidence: 98%

“…OCD can be classified as a juvenile form that presents prior to physeal closure, and an adult form in skeletally mature patients 2 , 3 . Juvenile OCD has a better prognosis than adult OCD, with higher rates of spontaneous healing under conservative therapy 4 . The treatment of OCD is also largely influenced by the stability of the progeny and parent bone.…”

Section: Introductionmentioning

confidence: 99%

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Bioabsorbable Unsintered Hydroxyapatite/Poly-l-Lactic Acid Pin Fixation of Osteochondritis Dissecans in Adolescents: Initial Experiences

et al. 2020

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Background This study sought to retrospectively evaluate the clinical and magnetic resonance imaging (MRI) outcomes of u-HA/PLLA pin (u-HA/PLLA: hydroxyapatite/poly-L-lactic acid) pin fixation of unstable osteochondritis dissecans (OCD) lesions of the knee. Methods Seven adolescent patients (four females and three males) with arthroscopically unstable OCD lesions of the knee were included. The mean age at diagnosis was 13.1 years. Clinical results were evaluated preoperatively and during follow-up using the Ogilvie-Harris score (0 – 15 points). MRI scans were performed preoperatively and during follow-up, with results evaluated using the Dipaola classification (grades 1 – 4). Mean follow-up time was 29 months. Results The median Ogilvie-Harris score improved from 13 points (range: 10 – 14 points) to 15 points (range: 13 – 15 points). Separately, the median Dipaola score improved from 3 points (range: 2 – 4 points) to 1 point (range: 1 – 4 points). No complications such as infection, synovitis, or intra-articular adhesion were observed. Conclusions Initial experiences using bioabsorbable u-HA/PLLA pins for the refixation of unstable OCD lesions in adolescents in the knee are promising, and MRI provides excellent monitoring of healing.

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“…Consequently, we did not observe inflammation, seroma formation, or other major complications in our study cohort. This was also true in prior comparable studies 4 , 9 .…”

Section: Discussionsupporting

confidence: 79%

Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

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Bioabsorbable Unsintered Hydroxyapatite/Poly-l-Lactic Acid Pin Fixation of Osteochondritis Dissecans in Adolescents: Initial Experiences

et al. 2020

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“…One proposed mechanism is that repetitive trauma leads to progression of the disease. This is supported by the findings that 55 to 60% of patients are involved regularly in sporting or athletic activities [88] [89] [90]. Additionally, repetitive contact with the tibial spine has been proposed as the etiology for OCD at the classic location on the medial condyle [84].…”

Section: Osteochondritis Dissecansmentioning

confidence: 86%

Cartilage diseases

2018

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Hyaline cartilages, fibrocartilages and elastic cartilages play multiple roles in the human body including bearing loads in articular joints and intervertebral discs, providing joint lubrication, forming the external ears and nose, supporting the trachea, and forming the long bones during development and growth. The structure and organization of cartilage's extracellular matrix (ECM) are the primary determinants of normal function. Most diseases involving cartilage lead to dramatic changes in the ECM which can govern disease progression (e.g., in osteoarthritis), cause the main symptoms of the disease (e.g., dwarfism caused by genetically inherited mutations) or occur as collateral damage in pathological processes occurring in other nearby tissues (e.g., osteochondritis dissecans and inflammatory arthropathies). Challenges associated with cartilage diseases include poor understanding of the etiology and pathogenesis, delayed diagnoses due to the aneural nature of the tissue and drug delivery challenges due to the avascular nature of adult cartilages. This narrative review provides an overview of the clinical and pathological features as well as current treatment options available for various cartilage diseases. Late breaking advances are also described in the quest for development and delivery of effective disease modifying drugs for cartilage diseases including osteoarthritis, the most common form of arthritis that affects hundreds of millions of people worldwide.

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“…MR arthrography is not frequently used, and intravenous contrast is controversial and generally avoided in children. 39 40 41 Griffith et al 42 implemented the widely used five-stage classification. The cut-off for instability was determined as the presence of fluid between the parent bone and the OCD fragment (stage 3).…”

Section: Osteochondral Lesionsmentioning

confidence: 99%

Postsurgical Evaluation of the Pediatric Foot and Ankle

Gómez

Bazzocchi

Simoni

et al. 2022

Semin Musculoskelet Radiol

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This article reviews situations in which surgical treatment is required in the context of different types of pathology in the foot and ankle of children, focusing on the role of imaging in surgical planning and postsurgical assessment. The types of pathology analyzed from this perspective are congenital pathology, neuromuscular disorders, osteochondral lesions, fractures and infection, ligament injuries, and tumors.We address the most common pitfalls of postsurgical imaging of the ankle and foot in children. With some exceptions, postsurgical follow-up focuses on clinical assessment, with imaging follow-up only needed in patients where complications are suspected or symptoms recur. Postoperative assessment of the foot and ankle in children and adolescents requires knowing the indications for surgery and the most common types of interventions, along with their imaging characteristics. The radiologist needs to be aware of the normal sequence of development of structures and how to select adequate imaging techniques to assess anatomy at various stages or in different postsurgical scenarios.

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Osteochondritis Dissecans

Cited by 50 publications

References 0 publications

Bioabsorbable Unsintered Hydroxyapatite/Poly-l-Lactic Acid Pin Fixation of Osteochondritis Dissecans in Adolescents: Initial Experiences

Bioabsorbable Unsintered Hydroxyapatite/Poly-l-Lactic Acid Pin Fixation of Osteochondritis Dissecans in Adolescents: Initial Experiences

Cartilage diseases

Postsurgical Evaluation of the Pediatric Foot and Ankle

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