Osteoporosis in men

Gielen, Evelien; Vanderschueren, Dirk; Callewaert, Filip; Boonen, Steven

doi:10.1016/j.beem.2010.08.012

Cited by 74 publications

(62 citation statements)

References 96 publications

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“…T 3 'ün nükleer reseptörlere bağlanması osteoblastları stimüle eder ve alkalen fosfataz, osteokalsin ve propeptid tip 1 kollajen gibi kemik yapım belirteçlerinin üretimine neden olur. Bu osteoblastik aktivite, osteoklastların T 3 aktivasyonuna aracılık eder ve böylece kemik yıkımına ve yıkım belirteçlerinin (kollajen çapraz bağları gibi) salınmasına neden olur (2). Artmış osteoklastik aktivite, kortikal ve trabeküler kemik kaybına neden olur ve sekonder osteoporoz gelişir.…”

Section: Discussionunclassified

“…Pek çok çalışmada, kemik devrini artıran hipertiroidide bu kemik kollajen yapısında yer alan piridinyum çapraz bağlarının idrardaki düzeylerinin artmış olduğu gözlenmiştir (7). Vertebra kompresyon kırıklarının %14'ü ve kalça kırıklarının %30'u erkeklerde görülmektedir ve önemli bir oranda morbidite ve mortaliteye sebep olmaktadır (2). Vertebral kırıklardan sonra mortalite genel popülasyonla karşılaştırıldığında %19 ve vertebral kırığı olmayan kişilerle karşılaştırıldığında %23-60 oranında artmaktadır.…”

Section: Discussionunclassified

“…En sık tespit edilen nedenler arasında aşırı alkol alımı, glukokortikoid fazlalığı (endojen veya ekzojen), hipogonadizm (primer veya sekonder) bulunmakta iken hipertiroidizm ise daha nadir sekonder osteoporoz sebeplerinden biridir (2). Tiroid hormonları kemik mineral homeostazında ve kemik yoğunluğunda önemli rol oynamaktadır.…”

Section: Introductionunclassified

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Vertebral Compression Fracture in a Patient with Hyperthyroidism

Kul¹,

Seferoglu²,

Şenel³

et al. 2016

Tod

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SummaryOsteoporosis in men is an important public health problem, and its prevalence is increasing as the population ages. Although it is traditionally considered as a women's health issue, osteoporosis-related mortality and morbidity rates are higher in men. Although the lifetime risk of the hip fracture is lower in men than women, men are twice as likely to die after a hip fracture. All men diagnosed with osteoporosis should be evaluated for secondary causes of bone loss, such as hypogonadism, the use of corticosteroid, smoking, excessive alcohol consumption, low calcium intake, vitamin D deficiency and hypothyroidism. Here, we aimed to present a male patient in whom osteoporotic a vertebral fracture was detected and who was diagnosed with hyperthyroidism. Keywords: Vertebral compression fracture, hyperthyroidism, osteoporosis Hipertiroidizm Tanısı Konan Bir Hastada Osteoporoza Bağlı Vertebral Kompresyon Fraktürü Vertebral Compression Fracture in a Patient with HyperthyroidismErkeklerde osteoporoz önemli bir halk sağlığı sorunudur ve yaşlı popülasyon arttıkça görülme sıklığı artmaktadır. Osteoporoz geleneksel olarak kadın sağlığı sorunu olarak kabul edilmesine rağmen, osteoporoz ilişkili mortalite ve morbidite oranları erkeklerde daha yüksektir. Yaşam boyu kalça kırığı riski erkeklerde kadınlardan daha düşük olmasına rağmen, kalça kırığı sonrası mortalite erkeklerde iki kat fazladır. Osteoporoz tanısı konulan bütün erkeklerde sekonder neden olarak hipogonadizm, kortikosteroid kullanımı, sigara, aşırı alkol tüketimi, düşük kalsiyum alımı, D vitamini eksikliği ve hipotiroid gibi nedenler araştırılmalıdır. Burada osteoporotik vertebra kırığı tespit edilen ve hipertiroidizm tanısı koyduğumuz erkek olguyu sunmayı amaçladık. Anahtar kelimeler: Vertebra kompresyon fraktürü, hipertiroidizm, osteoporoz Öz

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Section: Discussionunclassified

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Vertebral Compression Fracture in a Patient with Hyperthyroidism

Kul¹,

Seferoglu²,

Şenel³

et al. 2016

Tod

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“…9 It affects not only women but also men, a frequently under-recognized fact. 10,11 Osteoporotic fractures in men, although less frequent than in women, are associated with a higher mortality. 12,13 Following the diagnosis of an osteoporotic fracture, in addition to clinical evaluation and risk factors assessment (e.g.…”

Section: Causes Of Bone Loss In Menmentioning

confidence: 99%

“…In men, 50% of cases are secondary to one of three conditions: endogenous or exogenous glucocorticoid excess, hypogonadism, and excessive alcohol consumption. 10,11 In addition to these, idiopathic hypercalciuria-defined as urinary calcium > 3-4 mg/kg/day or 300 mg/24 h-is present in 8% of men with osteoporosis.…”

Section: Causes Of Bone Loss In Menmentioning

confidence: 99%

Bone Loss in Obesity and Obstructive Sleep Apnea: A Review of Literature

Chakhtoura

Nasrallah

Chami

2015

Journal of Clinical Sleep Medicine

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Age‐ and gender‐related variations in morphometric characteristics of thoracic spine pedicle

et al. 2013

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Transpedicular spinal fusion is the most commonly used fixation technique for the surgical treatment of vertebral disorders. However, the instrumentation of the thoracic spine using this technique continues to be controversial. The objective of the present study was to determine the morphometric characteristics of the thoracic pedicle and to establish how these characteristics vary with gender and age. Two hundred thoracic spines (4800 thoracic pedicles) from individuals of known gender and age were analyzed (in accordance with the order of vertebrae). The spines were divided into six groups according to age and gender. The horizontal and vertical diameters of the thoracic pedicle were determined for each piece. The mean and standard deviation of each variable were determined, and differences between age groups for each gender were evaluated using parametric correlation tests. The pedicle diameters of men and women differed significantly for most groups (P < 0.05). The horizontal diameters decreased from T1 to T5 and increased up to T12. The vertical diameter followed a cephalocaudal pattern of development from T1-T12. The pedicle diameters decreased with increasing age in women, while the opposite trend was observed in men. In men, the dimensions of the thoracic spine pedicle increase with increasing age; in women, they decrease. These differences should be taken into account when selecting the appropriate pedicle screw.

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Osteoporosis in men

Cited by 74 publications

References 96 publications

Vertebral Compression Fracture in a Patient with Hyperthyroidism

Vertebral Compression Fracture in a Patient with Hyperthyroidism

Bone Loss in Obesity and Obstructive Sleep Apnea: A Review of Literature

Age‐ and gender‐related variations in morphometric characteristics of thoracic spine pedicle

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