Osteosarcoma presenting as an aggressive nodular mass in the region of the mandible

Ong, Siew-Tin; Shim, Chen-Kiong; Ng, K.K.; Siar, Chong Huat

doi:10.2334/josnusd.46.55

Cited by 18 publications

(14 citation statements)

References 11 publications

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“…In a relatively short time the affected patients present paresthesias, initial mobility and then loss of the tooth. These clinical non-specific symptoms are similar to some benign tumors, malign tumors and infective disease (osteoblastoma, ossifying fibroma, fibrous dysplasia and infective pathologies like osteomyelitis with proliferative periostitis, suppurative osteomyelitis) [1][2][3][4][5][6][7].…”

Section: Discussionmentioning

confidence: 99%

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Local invasion of jaw osteosarcoma

Fiori¹,

Vivo²,

Scarano³

et al. 2015

IJCRI

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International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties.Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations. One of the most common primary malignant bone tumor is osteosarcoma that counts high percentages in the level of incidence the 5% of all tumor in children, and the 9% of all sarcomas. Osteosarcoma are malignant bone tumors developing from mesenchymal tumor cells that growth as disorganized immature bone or osteoid tissue. Patients affected by osteosarcoma show a peak incidence related to puberty (for young female 12±2 years and for young male 16±1.8 years). Regardless of the favorable biological behaviour, the patients of jaw osteosarcoma usually exhibit advanced tumor as it often goes unnoticed by the dental professional thus stressing on the need for early diagnosis of the lesion. Case Report: We report an unusual case history of a 34-year-old male with swelling and blood loss in anterior gingival of maxilla with loss of teeth. Conclusion:There are three main methods to diagnose the tumor based on clinical and radiographic characteristics before confirmation by histology and to bring attention to dental professional to approach cases diagnosing them at an early stage leading to better prognosis.

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Section: Discussionmentioning

confidence: 99%

“…The gold standard is an early diagnosis in order to prevent its continuous infiltrative growth [6]. Osteosarcoma usually metastasizes through the blood such as mesenchymal malignancy.…”

Section: Introductionmentioning

confidence: 99%

Local invasion of jaw osteosarcoma

Fiori¹,

Vivo²,

Scarano³

et al. 2015

IJCRI

View full text Add to dashboard Cite

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“…Osteosarcoma is a common primary malignancy of bone, but is a relatively rare disease in the orofacial region (8,9). …”

Section: Discussionmentioning

confidence: 99%

<b>Unusual Case of Maxillary Osteosarcoma in a 12-year-old Child: A Case Report </b>

et al. 2015

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Osteosarcoma is a malignancy of mesenchymal cells, which have the ability to produce osteoid or immature bone. Osteosarcoma is the most common malignancy originating within bone, but occurs very infrequently in the jaws, comprising only 4% of the number of osteosarcomas of the long bones. Maxillary osteosarcoma presents with common clinical features of pain and swelling. Here we present a rare case of maxillary osteosarcoma in a 12-year-old girl. Diagnosis and preoperative assessment were performed using a combination of conventional radiography and advanced imaging. The aim of this case report is to draw attention to the possibility of diagnosing this tumor based on clinical and radiographic characteristics.

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“…Further, in the fifth and sixth decades, they are frequently secondary to either radiation therapy or transformation in a pre existing benign condition, such as Paget's disease (3). There is no gender preponderance in osteosarcoma (3) while some authors state that males are affected 1.5 to 2 times as often as females (2). It has a predilection for metaphyses of long bones and the most common sites of involvement are the distal femur, proximal tibia, and proximal humerus (3).…”

Section: Introductionmentioning

confidence: 99%

“…It is a spindle cell neoplasm and accounts for almost 40-60% of all bone sarcomas (2). About 60% of all osteosarcomas occur in the second decade of life in children and adolescents, and about 10% occur in the third decade.…”

Section: Introductionmentioning

confidence: 99%

Osteosarcoma of maxilla: A case report

Sheikh¹,

Pallagatti²,

Aggarwal³

et al. 2010

J Clin Exp Dent

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Osteosarcoma is a common primary malignant bone tumor producing osteoid or bone. It occurs very infrequently in the jaws and comprises of 4% of the tumour number as compared to the osteosarcoma of the long bones. Osteosarcoma of the maxilla is even rarer presenting with common clinical features of pain and swelling. This presented case is a rare case of osteosarcoma of maxilla in a 21-year-old female patient. Diagnosis and pre-operative assessment was performed using a combination of intraoral periapical radiograph, occlusal radiograph, paranasal view and computed tomography (CT). CT revealed destruction of the walls of maxillary sinus and sunray type of ossification in the soft tissues. Conformation was done with histology report followed by surgical removal of the tumor with safety margins. Dental professionals may be the first to detect jaw osteosarcomas in their initial stages. Regardless of the favourable biological behaviour, the patients of jaw osteosarcoma usually exhibit advanced tumor as it often goes unnoticed by the dental professional thus stressing on the need for early diagnosis of the lesion. The aim of this case report is to draw attention to the possibility of diagnosing this tumor based on clinical and radiographical characteristics before confirmation by histology.

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Osteosarcoma presenting as an aggressive nodular mass in the region of the mandible

Cited by 18 publications

References 11 publications

Local invasion of jaw osteosarcoma

Local invasion of jaw osteosarcoma

<b>Unusual Case of Maxillary Osteosarcoma in a 12-year-old Child: A Case Report </b>

Osteosarcoma of maxilla: A case report

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