Osteosynthesis associated contact dermatitis with unusual perpetuation of hyperreactivity in a nickel allergic patient

Thomas, Peter A.; Gollwitzer, Hans; Maier, S.; Ruëff, Franziska

doi:10.1111/j.0105-1873.2006.0775j.x

Cited by 20 publications

(8 citation statements)

References 18 publications

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“…This was observed particularly in patients with extremity osteosynthesis that was sensitive to nickel or cobalt (Schuh et al 2008) and in patients with cerclage after sternotomy. A case report pointed to potential hyper-reactivity to metal close to the skin (Thomas et al 2006). In a recent study conducted on 233 patients in a hospital specializing in implant allergies, it was found that 75% of patients with complications were arthroplasty patients.…”

Section: Discussionmentioning

confidence: 99%

Pain in a chromium-allergic patient with total knee arthroplasty: disappearance of symptoms after revision with a special surface-coated TKA — a case report

Thomsen¹,

Rozak²,

Thomas

2011

Acta Orthopaedica

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Section: Discussionmentioning

confidence: 99%

Pain in a chromium-allergic patient with total knee arthroplasty: disappearance of symptoms after revision with a special surface-coated TKA — a case report

Thomsen¹,

Rozak²,

Thomas

2011

Acta Orthopaedica

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“…This was assumed to be due to a broken drill left at the fracture site. During the course of the skin disease, this patient also developed clinical evidence of metal sensitivity 130 …”

Section: The Mechanism Of Systemic Contact Dermatitismentioning

confidence: 89%

Systemic contact dermatitis

Veien¹

2011

Int J Dermatology

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Systemic contact dermatitis is an inflammatory skin disease that may occur in persons with contact allergy when they are exposed to the hapten orally, transcutaneously, per rectum, intravesically, intravenously, or by inhalation. The most common causes of systemic contact dermatitis are drugs used both topically and systemically. Other causes are ubiquitously occurring haptens, such as the metals nickel, cobalt, gold, and chromate, and aromatic substances such as spices. Avoidance of the offending hapten is the most obvious treatment. For some haptens, such as nickel, diet treatment may be effective. Chelation therapy with disulfiram is another therapeutic option in nickel-allergic patients with systemic contact dermatitis. Hyposensitization therapy has been attempted with some success in systemic contact dermatitis caused by nickel and Parthenium hysterophorus.

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“…Diese können sich als lokale oder generalisierte Hautveränderungen, Wundheilungsstö-rung, wiederkehrende Schmerzen oder Abb. 3 [21]. Hierzu passt der Bericht über eine Patientin mit Wundheilungsstörung und lokalem Ekzem nach einer Titanosteosynthese [23].…”

Section: » Bei Komplikationsbehaftetenunclassified

Klinik und Histologie Metallimplantat-assoziierter Hauterscheinungen

et al. 2016

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Metal implant sensitivity (intolerance) can cause pain, reduced mobility, loosening of the implant and skin rashes. Knowledge of differential diagnoses, histology and appropriate diagnostics are essential for proper diagnosis. To outline typical clinical signs and histology in metal-implant-associated skin lesions we present three exemplary patients from our implant allergy outpatient department and give an overview of the current literature regarding metal implant sensitivity. In patients with a negative patch test the lymphocyte transformation test may reveal metal sensitization. Even "pure" titanium alloys may contain traces of nickel. The histology of implant-associated skin reactions goes from teleangiectatic postimplantation erythema to eczema and vasculitis. Based on the synopsis of history, clinical picture, allergological testing and histology, metal implant sensitivity can be diagnosed more precisely.

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Osteosynthesis associated contact dermatitis with unusual perpetuation of hyperreactivity in a nickel allergic patient

Cited by 20 publications

References 18 publications

Pain in a chromium-allergic patient with total knee arthroplasty: disappearance of symptoms after revision with a special surface-coated TKA — a case report

Pain in a chromium-allergic patient with total knee arthroplasty: disappearance of symptoms after revision with a special surface-coated TKA — a case report

Systemic contact dermatitis

Klinik und Histologie Metallimplantat-assoziierter Hauterscheinungen

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Osteosynthesis associated contact dermatitis with unusual perpetuation of hyperreactivity in a nickel allergic patient

Cited by 20 publications

References 18 publications

Pain in a chromium-allergic patient with total knee arthroplasty: disappearance of symptoms after revision with a special surface-coated TKA ­— a case report

Pain in a chromium-allergic patient with total knee arthroplasty: disappearance of symptoms after revision with a special surface-coated TKA ­— a case report

Systemic contact dermatitis

Klinik und Histologie Metallimplantat-assoziierter Hauterscheinungen

Contact Info

Product

Resources

About

Pain in a chromium-allergic patient with total knee arthroplasty: disappearance of symptoms after revision with a special surface-coated TKA — a case report

Pain in a chromium-allergic patient with total knee arthroplasty: disappearance of symptoms after revision with a special surface-coated TKA — a case report