2014
DOI: 10.1039/c4fd90077d
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Other Nanoparticles: general discussion

Abstract: Sara Carreira opened the discussion of the paper by Nicolas Barry: Why are your RuMs and OsMs so specic to cancer cells without using any targeting moiety?Nicolas Barry replied: We believe that the specicity comes from the size of the particles -passive targeting. Clinically-validated therapeutic and imaging NPs usually target cancer cells in a passive way. This is achieved by taking advantage of the enhanced permeability and retention (EPR) effect in tumor tissues. Tumor vasculature is highly disorganised, … Show more

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