Other transgenic mutation assays: Tissue specificity of spontaneous point mutations in λsupF transgenic mice

Moderate Hypermutability of a Transgenic lacZ Reporter Gene in Myc -Dependent Inflammation-Induced Plasma Cell Tumors in Mice

“…Among the many advantages of the mouse is the ability to assess mutations in vivo using transgenic shuttle vectors with a bacterial reporter gene. Several transgenic reporter systems for measuring mutation frequency in vivo have been developed (7)(8)(9)(10)(11). Two widely used systems rely on the phage vector, LIZ (12,13), or the plasmid vector, pUR288 (14).…”