Otitis media, classification and treatment features

Koçyiğit, Murat; Örtekin, Safiye Giran; Çakabay, Taliye

doi:10.5222/iksst.2016.065

Cited by 4 publications

(5 citation statements)

References 16 publications

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“…The most frequently accused factor in OME aetiopathogenesis is the inflammatory hypothesis 7,17 . Chronic inflammation caused by viral and bacterial infections in the middle ear and accompanied by eustachian tube dysfunction leads to fluid secretion from the middle ear epithelium 7,14,18,19 . This effusion is rich in protein and inflammatory mediators 19 .…”

Section: Discussionmentioning

confidence: 99%

“…7,17 Chronic inflammation caused by viral and bacterial infections in the middle ear and accompanied by eustachian tube dysfunction leads to fluid secretion from the middle ear epithelium. 7,14,18,19 This effusion is rich in protein and inflammatory mediators. 19 The effusion that accumulates in the middle ear may be serous or mucoid, but it is not purulent.…”

Section: Discussionmentioning

confidence: 99%

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Neutrophil‐lymphocyte and platelet‐lymphocyte ratios in otitis media with effusion in children: Diagnostic role and audiologic correlations

2020

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Aim To investigate the relationship between hearing loss and complete blood count parameters including neutrophil, lymphocyte, platelet (PLT), mean platelet volume (MPV), neutrophil‐lymphocyte ratio (NLR) and platelet‐lymphocyte ratio (PLR) in children with otitis media with effusion (OME). Materials‐Method The study group was formed by 244 paediatric patients who underwent ventilation tube placement because of OME, and was split into two groups as serous and mucoid. The control group included 112 individuals who have no hearing problems. Hearing levels were determined with pure tone audiometry in the study group, preoperatively, and control group. The blood parameters were compared between the serous, mucoid and control groups. The correlation analysis was performed between the blood parameters and hearing levels in the study group. The blood parameters were compared between the groups identified by hearing loss classification. Findings There were significant negative correlations between hearing levels and each of NLR, PLR and MPV. There were significant positive correlations between hearing levels and each of the lymphocyte and PLT. According to the receiver operating characteristic (ROC) curves, serous OME can be estimated with 68% sensitivity and 61% specificity by the NLR value more than 1.1, and 77% sensitivity and 77% specificity by the PLR value more than 102.4. The ROC curve revealed that slight hearing loss could be estimated with 70% sensitivity and 73% specificity by the NLR value more than 1.31, and 78% sensitivity and 77% specificity by the PLR value more than 102.4. Conclusion The present study revealed that NLR and PLR values were valuable parameters in the diagnosis of serous OME and predicting a hearing loss. These parameters may provide additional information to the audiogram that could influence the therapeutic decision.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Neutrophil‐lymphocyte and platelet‐lymphocyte ratios in otitis media with effusion in children: Diagnostic role and audiologic correlations

2020

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“…Bu enfeksiyonların büyük çoğunluğu viral olmasına karşın AOM bakteriyel bir enfeksiyon olarak kabul edilmektedir. Östaki tüpünün ödem veya negatif intratimpanik basınçla etkilenmesi, buradaki mukosiliyer aktiviteyi bozarak, enfeksiyonun farenks yoluyla timpanik kaviteye doğrudan yayılmasına ve AOM oluşmasına neden olmaktadır (9) . Çalışmamızda otit tanısı alan hastaların 11526'sında (%47.6) AOM vardı.…”

Section: Discussionunclassified

“…SOM, çoğunlukla östaki tüpündeki fonksiyon bozukluğu sonucu oluşur ve AOM gibi daha çok bebeklerde ve çocuklarda görülür (9,10) . Östaki tüpü, basınç regülasyonu ile orta kulak ventilasyonunu, nazofarenks ve üst solunum yolu sekresyonlarının orta kulağa geçişini engelleyerek korunmasını ve orta kulakta üretilen mukusun drenajını sağlayarak temizliğini sağlar.…”

Section: Discussionunclassified

Retrospective Analysis of Patients Diagnosed with Otitis Clinically in Our Clinic

Koçyiğit¹,

Örtekin²

2017

IKSST

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“…Acute Otitis media (AOM), which defines the inflammation of the tympanic cavity, the Eustachian tube, the mastoid process and the mucoperiosteum surrounding the mastoid air cells, is recognized as one of the most important animal and human health threatening infectious diseases across the world ( 1 , 2 ). Given the anatomical localization of the ear, AOM should be evaluated in terms of many different complications, extracranial and/or intracranial ( 3 , 4 , 5 , 6 ).…”

Section: Introductionmentioning

confidence: 99%

Three-Dimensional Analysis of Round Window Membrane in the Chinchilla Model with Acute Otitis Media Induced with <i>Streptococcus Pneumoniae</i> 7F

Keskin

Albasan²,

Börkü

et al. 2021

TAO

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Objective: The purpose of this study was to investigate the morphological changes of round window membrane (RWM) in chinchillas with Streptococcus pneumoniae (S. pneumoniae) serotype 7F induced acute otitis media (AOM) by two dimensional (2D) and three dimensional (3D) measurements. Methods: Temporal bone specimens taken from 12 chinchillas were divided into two groups. The control group consisted of healthy animals that were injected with intrabullar saline. The subjects in the experimental group were induced with AOM by intrabullar injection of S. pneumoniae 7F. The 2D and 3D measurements of RWM were compared between the groups. Results: Dramatic changes were noted in the RWM of the experimental group compared to the control group. The thickness [mean ± standard deviation (SD)] of the RWM was significantly (p<0.05) increased in the experimental group compared to the control group by 2D measurements taken at three different points of RWM. Moreover, 3D measurements revealed that the volume (mean ± SD) of RWM was significantly (p=0.009) increased in the experimental group. Conclusion: The results of our study, which indicated significant change in RWM in both 2D and 3D measurements, may shed light on the relationship between AOM and inner ear diseases. Based on our results, we recommend evaluating 3D analyses of RWM, which provide useful data, to better understand the changes in the membrane.

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Otitis media, classification and treatment features

Abstract: Derleme ÖZOtitis media (OM)

Cited by 4 publications

References 16 publications

Neutrophil‐lymphocyte and platelet‐lymphocyte ratios in otitis media with effusion in children: Diagnostic role and audiologic correlations

Neutrophil‐lymphocyte and platelet‐lymphocyte ratios in otitis media with effusion in children: Diagnostic role and audiologic correlations

Retrospective Analysis of Patients Diagnosed with Otitis Clinically in Our Clinic

Three-Dimensional Analysis of Round Window Membrane in the Chinchilla Model with Acute Otitis Media Induced with <i>Streptococcus Pneumoniae</i> 7F

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