Our Efforts for Ideal Stroke Prevention and Treatment in Japan

Abstract

In the present short review for the Sherman Award, Dr Yamaguchi introduces studies at the National Cerebral and Cardiovascular Center, Osaka, which included development of intravenous thrombolysis using low-dose alteplase that was officially approved in Japan, long-term dual antiplatelet therapy using cilostazol together with aspirin or clopidogrel, and others. He also discusses efforts to ensure the passage of the “Stroke and Cardiovascular Disease Control Act,” the aims of which are better primary prevention, better acute treatment, rehabilitation, and secondary prevention of stroke for people living in Japan.

Understanding Antithrombotic Agents for Rehabilitation Therapy: A Comprehensive Narrative Review

“…Recently, new antithrombotic agents and their neutralizers/antagonists have been introduced, and guidelines reflecting these new findings have been published one after another in the fields of cardiovascular and cerebrovascular disorders [ 3 ]. In daily practice, antithrombotic agents should be used in consideration of the above background and treatment guidelines [ 4 ].…”

“…Recently, new antithrombotic agents and their neutralizers/antagonists have been introduced, and guidelines reflecting these new findings have been published one after another in the fields of cardiovascular and cerebrovascular disorders [3]. In daily practice, antithrombotic agents should be used in consideration of the above background and treatment guidelines [4]. This article reviews the pharmacological effects of antithrombotic agents as basic knowledge, and the precautions to be taken when prescribing them in daily clinical practice, with a focus on ischemic cerebrovascular disease (ICD).…”