Polypharmacy is a common problem among older adults, as they are more likely to have multiple chronic conditions and may experience fragmentation of care among specialists. The Geriatrics 5Ms framework offers a person-centered approach to address polypharmacy and optimize medications, including deprescribing when appropriate. The elements of the Geriatrics 5Ms, which align with the approach of the Age-Friendly Health Systems initiative, include consideration of Medications, Mind, Mobility, Multicomplexity, and What Matters Most. Each M domain impacts and is impacted by medications, and learning about the patient's goals through questions guided by the Geriatrics 5Ms may inform an Age-Friendly medication optimization plan. While research on the implementation of each of the elements of the Geriatrics 5Ms shows benefit, further research is needed to study the impact of this framework in clinical practice.
Key PointsThe Geriatrics 5Ms of Mobility, Mind, Medications, Multicomplexity, and What Matters Most can help clinicians address polypharmacy among older adults, by addressing how each M domain impacts and is impacted by Medications.The Age-Friendly Health Systems approach to medication management can help align medication use with what matters to the patient.Further research is needed to study the impact of an Age-Friendly approach to polypharmacy in older adults and others across the lifespan.