Outcome of Children With Hematologic Malignancy Who Are Admitted to an Intensive Care Unit

The intensive care unit in paediatric oncology.

“…Most are applicable only to adult oncology units, and there is a large variation in results and the conclusions drawn from these studies.2-5 The only similar paediatric report comes from a combined study of three hospitals in Australia and Canada. 6 The overall survival for all children in this study was 51%. The mortality was higher for those children who required ventilation, where there was only a 30% survival.…”

“…Our experience is similar to that described by Butt et al who also reported a high mortality for these patients. 6 We reviewed in detail the case notes of the septicaemic patients in an attempt to identify factors that may have contributed to the patients' deaths. Factors examined included the time from the onset of marked cardiovascular symptoms to the use of inotropes, the subsequent time to admission to the ICU and to intubation, the indications for intubation, and the time the patient died.…”

Outcomes of stem cell transplant patients with acute respiratory failure requiring mechanical ventilation in the United States

“…[7][8][9][10] In oncologic patients, acute respiratory failure (ARF) is the most common cause of ICU admission and the leading non-relapse cause of mortality following chemotherapy or BMT. [11][12][13] Need for mechanical ventilation is a major determinant of prognosis in oncology patients with an ICU mortality exceeding 75% for patients who have respiratory failure associated with ARDS. [14][15][16][17] Approximately 25% of all BM recipients ultimately require mechanical ventilation for respiratory failure, usually within 60 days of marrow infusion.…”

Comparação dos diferentes escores de gravidade utilizados em unidade de terapia intensiva pediátrica oncológica

“…para aqueles que necessitam de suporte ventilatório ou inotrópico no contexto da sepse ou após o TMO (Butt et al, 1988;Sivan, 1991;Meert et al, 1991;Heney et al, 1992;Abraham et al 2002). Butt et al (1988) descreveram uma taxa de mortalidade de 75% para pacientes com falência respiratória ou circulatória e > 85% quando o suporte respiratório ou inotrópico foi necessário.…”

“…Butt et al (1988) descreveram uma taxa de mortalidade de 75% para pacientes com falência respiratória ou circulatória e > 85% quando o suporte respiratório ou inotrópico foi necessário. Para os colegas intensivistas pediátricos, o benefício da UTIP para muitas dessas crianças com neoplasias continua a ser debatida (Orlowski et al, 1989 (Butt, 1988;Sivan, 1991), sendo que no caso de pacientes pós TMO essas taxas se aproximaram de 90% (DeNardo et al, 1989;Afessa et al, 1992;Crawford et al, 1992;Todd et al, 1994;Nichols et al, 1994).…”