Outcome of Patients with End Stage Renal Disease Admitted to an Intensive Care Unit in India

Juneja, Deven; Prabhu, Mayoor V.; Gopal, Palepu; Mohan, Sanil; Sridhar, G. R.; Nayak, K.S.

doi:10.3109/08860220903367502

Cited by 22 publications

(34 citation statements)

References 17 publications

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“…4 Devan juneja et al, study during 2010 on outcome of patients with end stage renal disease admitted to an intensive care unit, 73 patient they observed and mean APACHE II score were 26 (14-49), SOFA score were 7(4-17). 8 In M P Halle et al, study mean sofa score in survivors were 6 and non survivors were 8.In present study mean sofa score were 8.8 ± 2.5.…”

Section: Severity Of Acute Pulmonary Edemasupporting

confidence: 46%

Acute pulmonary oedema in chronic dialysis patients, causes, clinical course and outcome admitted into emergency department

Jimnaz¹,

Kharim²

2017

Int J Adv Med

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Background: Chronic dialysis (CD) patient are at increased risk of multiple organ dysfunction. Recent study, estimated that 2% of CD patients require intensive care unit (ICU) admission every year. Acute Pulmonary Oedema is major cause for ICU admissions, objective of the study is to determine the cause, clinical course and outcome of APO in CD patients admitted in Intensive Care Units under Emergency Department.Methods: Prospective and observational study conducted for 1 year in our institute, a tertiary care centre, was done on chronic dialysis(CD) who presented with Acute pulmonary oedema(APO) for determine cause for APO, severity of outcome by APACHE II and sofa score. Data was entered in Microsoft Excel spread sheet and analyzed using SPSS software. Descriptive analysis and chi square test was done.Results: Study included 100 CD patients. Main etiologic factor of CKD was T2DM 56%. Etiology of APO in this study showed as 34% are due to excessive interdialytic weight gain. Only 4 patients were assessed by SOFA score and high sofa score no patients had expired. Study showed survived patients got mean APACHE II score of 24±3.4 and expired patients got mean APACHE II score of 32.9±2.5, with a significant P value <0.001.Conclusions: Main etiology of APO in CD patients were excessive interdialytic weight gain 34 %. APACHE II score as outcome predictors. APACHE II score of more than 30 have poor outcome

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Section: Severity Of Acute Pulmonary Edemasupporting

confidence: 46%

Acute pulmonary oedema in chronic dialysis patients, causes, clinical course and outcome admitted into emergency department

Jimnaz¹,

Kharim²

2017

Int J Adv Med

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“…As expected, physiological, and biochemical disturbances including hypotension, bradycardia, tachypnoea, hypoxia, reduced Glasgow Coma Score, hyponatraemia, leucopenia, and sepsis within the first 24 hours of ICU admission exert a significant impact on hospital mortality, too [4]. Mechanical ventilation and the need for inotropic support are also significantly associated with mortality at 30 days [13]. Whilst many of these variables are risk factors for mortality in ICU patients in general, their impact on the ESRD population appears to be greater, perhaps due to a lack of physiological reserve in this group.…”

Section: Longer-term Outcomesmentioning

confidence: 92%

“…Gastrointestinal bleeding is the third most common reason for chronic dialysis patients to require critical care, with studies estimating rates of 2.7% to 20% in critically unwell dialysis patients [7, 10, 13, 14]. …”

Section: Characteristics Of Critically Ill Dialysis Patientsmentioning

confidence: 99%

“…Hospital, 30-day, and 90-day mortality rates for critically ill chronic dialysis patients are estimated at 14% to 56% [4–8, 10, 11, 13, 14, 18, 21, 22], 32% to 41% [10, 13, 22], and 42% to 44.6% [12, 24], respectively. Hospital mortality rates were significantly higher in chronic dialysis patients compared to the non-ESRD population after ICU discharge (45.3% versus 31.2%, P < 0.001) [4].…”

Section: Longer-term Outcomesmentioning

confidence: 99%

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Outcomes of Chronic Hemodialysis Patients in the Intensive Care Unit

Chan

Ostermann

2013

Critical Care Research and Practice

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Patients with end-stage renal disease (ESRD) experience higher rates of hospitalisation, cardiovascular events, and all-cause mortality and are more likely to require admission to the intensive care unit (ICU) than patients with normal renal function. Sepsis and cardiovascular diseases are the most common reasons for ICU admission. ICU mortality rates in patients requiring chronic hemodialysis are significantly higher than for patients without ESRD; however, dialysis patients have a better ICU outcome than those with acute kidney injury (AKI) requiring renal replacement therapy suggesting that factors other than loss of renal function contribute to their prognosis. Current evidence suggests, the longer-term outcomes after discharge from ICU may be favourable and that long-term dependence on dialysis should not prejudice against prompt referral or admission to ICU.

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“…Dialysis patients are more likely to be admitted to the ICU for medical rather than surgical conditions [2,3]. The most frequent admission diagnoses for dialysis patients are related to sepsis and cardiovascular disease [3,4,8,9,10]. Interestingly, a number of studies have reported a higher rate of cardiac arrest prior to ICU admission in dialysis patients [11,12,13,14].…”

Section: Epidemiology Of Critical Illness In Dialysis Patientsmentioning

confidence: 99%

Renal Replacement Therapy in the End-Stage Renal Disease Patient with Critical Illness

Thompson¹,

Pannu

2012

Blood Purif

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Dialysis patients account for 1–9% of all intensive care unit (ICU) admissions. As a result of the increasing prevalence of patients with end-stage renal disease (ESRD) and the changing demographics of this population, the number of dialysis patients requiring hospitalization and ICU support is expected to increase. Critically ill ESRD patients have more comorbidity and higher severity of illness than the general population resulting in higher ICU and in-hospital mortality rates. ESRD patients have been excluded from trials evaluating renal replacement therapy in the ICU, therefore little information is available about the optimal management of renal replacement therapy for dialysis patients in this setting. This review focuses on the epidemiology of chronic dialysis patients admitted to the ICU and discusses an approach to providing renal replacement therapy for critically ill patients with ESRD.

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Outcome of Patients with End Stage Renal Disease Admitted to an Intensive Care Unit in India

Abstract: Outcome of ESRD patients admitted to ICU is poor, especially if they require other organ support. APACHE II and SOFA scores perform well as predictors of 30-day mortality.

Cited by 22 publications

References 17 publications

Acute pulmonary oedema in chronic dialysis patients, causes, clinical course and outcome admitted into emergency department

Acute pulmonary oedema in chronic dialysis patients, causes, clinical course and outcome admitted into emergency department

Outcomes of Chronic Hemodialysis Patients in the Intensive Care Unit

Renal Replacement Therapy in the End-Stage Renal Disease Patient with Critical Illness

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