Outcomes From a Modified Microkeratome-Assisted Lamellar Keratoplasty for Keratoconus

Busin, Massimo; Scorcia, Vincenzo; Zambianchi, Luca; Ponzin, Diego

doi:10.1001/archophthalmol.2011.1546

Cited by 37 publications

(41 citation statements)

References 28 publications

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“…Results of the first 100 procedures show acceptable outcomes in terms of graft clarity, visual acuity, astigmatism, and endothelial cell loss. Notable complications included buttonholing of the recipient bed necessitating conversion to penetrating keratoplasty and double anterior chamber formation 98. The procedure seems attractive because it does not seem to require exceptional surgical skill, has the potential to be standardized, and may provide outcomes similar to penetrating keratoplasty, without the risk of endothelial rejection.…”

Section: Managementmentioning

confidence: 99%

Keratoconus: current perspectives

Vazirani

Basu²

2013

OPTH

106

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Keratoconus is characterized by progressive corneal protrusion and thinning, leading to irregular astigmatism and impairment in visual function. The etiology and pathogenesis of the condition are not fully understood. However, significant strides have been made in early clinical detection of the disease, as well as towards providing optimal optical and surgical correction for improving the quality of vision in affected patients. The past two decades, in particular, have seen exciting new developments promising to alter the natural history of keratoconus in a favorable way for the first time. This comprehensive review focuses on analyzing the role of advanced imaging techniques in the diagnosis and treatment of keratoconus and evaluating the evidence supporting or refuting the efficacy of therapeutic advances for keratoconus, such as newer contact lens designs, collagen crosslinking, deep anterior lamellar keratoplasty, intracorneal ring segments, photorefractive keratectomy, and phakic intraocular lenses.

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Section: Managementmentioning

confidence: 99%

Keratoconus: current perspectives

Vazirani

Basu²

2013

OPTH

106

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“…More recently, Busin and colleagues described the modified ‘microkeratome‐assisted lamellar keratoplasty’ for keratoconus. The surgical technique is essentially the same as conventional microkeratome‐assisted anterior lamellar transplantation except that the surgeon performs a full‐thickness trephination of the recipient bed before suturing the donor graft in place (Figures and ).…”

Section: Special Corneal Graft Techniques For Keratoconusmentioning

confidence: 99%

Recent advances in corneal transplantation for keratoconus

Cassidy

Beltz

Jhanji

et al. 2013

Clinical and Experimental Optometry

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From the rise of modern corneal graft surgery in the late 1950s until recently, corneal transplantation for keratoconus almost exclusively consisted of a full-thickness transplant, termed penetrating keratoplasty. This technique involved the removal of all of the layers of the patient's central cornea and replacement with a full-thickness graft. Over approximately the past 20 years, a quiet revolution has occurred with the development of several other types of corneal transplantation surgery for keratoconus. In addition to full thickness grafts, several different types of partial thickness, lamellar grafts, have been developed and are viable alternatives to a full-thickness graft in selected patients. The main aim of these lamellar grafts is to selectively replace the corneal stroma, leaving intact the patient's own Desçemet's membrane and endothelial cells, the main target of allograft transplant rejection. In this article, we review the current options with regard to corneal transplantation for keratoconus and review the evidence comparing newer and more established techniques.

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“…The onset is during puberty and progresses until the third decade of the life when it usually becomes stable 2. There are variety of options for management of this pathological condition including, spectacles,2 rigid gas permeable, soft or hybrid contact lenses,3 intracorneal ring segments (ICRS),4568 collagen crosslinking (CXL)9 and lamellar or penetrating keratoplasty 10…”

Section: Introductionmentioning

confidence: 99%

Intrastromal corneal ring segments: How successful is the surgical treatment of keratoconus?

Alió

Vega-Estrada

Esperanza

et al. 2014

Middle East Afr J Ophthalmol

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This review evaluates the outcomes of intrastromal corneal ring segment (ICRS) implantation for the treatment of keratoconus considering a new grading system based on the preoperative visual impairment of the patient. Additionally, a five-year follow-up analysis of patients with stable and progressive keratoconus is performed in order to assess the long term stability of the surgical procedure. Corrected distance visual acuity decreased statistically significantly in patients with mild keratoconus (P < 0.01) but statistically significantly increased in all other grades (P < 0.05). The improvement in visual acuity and the decrease of keratometric and aberrometric values were stable throughout a long period of time in patients with stable keratoconus. In patients with progressive form keratoconus, a significant improvement was found immediately after the procedure, however clinically relevant regression greater than 3 D was observed at the end of the follow up period.

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Outcomes From a Modified Microkeratome-Assisted Lamellar Keratoplasty for Keratoconus

Cited by 37 publications

References 28 publications

Keratoconus: current perspectives

Keratoconus: current perspectives

Recent advances in corneal transplantation for keratoconus

Intrastromal corneal ring segments: How successful is the surgical treatment of keratoconus?

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