Outcomes of metabolic surgery in obese patients with type 2 diabetes with respect to impact on beta cell function, insulin sensitivity and diabetes remission - A study from south India

Chandru, Sundaramoorthy; Pramodkumar, Thyparambil Aravindakshan; Pradeepa, Rajendra; Muthukumar, Subramaniapillai; Balasubramanyam, Muthuswamy; Bhuvaneshwari, Raghavan; Mohan, Viswanathan

doi:10.1016/j.dsx.2020.09.010

Cited by 4 publications

(1 citation statement)

References 45 publications

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“…Spain hosts teams engrossed in metabolic surgery ( 60 ) and others probing the impact of dietary regimens on diabetes remission, exemplified by the CORDIOPREV study ( 61 ). In India, the majority of teams are engrossed in metabolic surgery ( 62 , 63 ). Danish research related to diabetes remission is likewise dominated by metabolic surgery ( 64 , 65 ).…”

Section: Discussionmentioning

confidence: 99%

Global research trends of diabetes remission: a bibliometric study

Yang,

He,

Chen

et al. 2023

Front. Endocrinol.

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BackgroundResearch on diabetes remission has garnered prominence in recent years. However, to date, no pertinent bibliometric study has been published. This study sought to elucidate the current landscape and pinpoint potential new research directions through a bibliometric analysis of diabetes remission.MethodsWe perused relevant articles on diabetes remission from January 1, 2000, to April 16, 2023, in the Web of Science. We utilized CiteSpace software and VOSviewer software to construct knowledge maps and undertake analysis of countries, institutional affiliations, author contributions, journals, and keywords. This analysis facilitated the identification of current research foci and forecasting future trends.ResultsA total of 970 English articles were procured, and the annual publication volume manifested a steady growth trend. Most of the articles originated from America (n=342, 35.26%), succeeded by China and England. Pertaining to institutions, the University of Newcastle in England proliferated the most articles (n=36, 3.71%). Taylor R authored the most articles (n=35, 3.61%), and his articles were also the most co-cited (n=1756 times). Obesity Surgery dominated in terms of published articles (n=81, 8.35%). “Bariatric surgery” was the most prevalently used keyword. The keyword-clustering map revealed that the research predominantly centered on diabetes remission, type 1 diabetes, bariatric surgery, and lifestyle interventions. The keyword emergence and keyword time-zone maps depicted hotspots and shifts in the domain of diabetes remission. Initially, the hotspots were primarily fundamental experiments probing the feasibilities and mechanisms of diabetes remission, such as transplantation. Over the course, the research trajectory transitioned from basic to clinical concerning diabetes remission through bariatric surgery, lifestyle interventions, and alternative strategies.ConclusionOver the preceding 20 years, the domain of diabetes remission has flourished globally. Bariatric surgery and lifestyle interventions bestow unique advantages for diabetes remission. Via the maps, the developmental milieu, research foci, and avant-garde trends in this domain are cogently portrayed, offering guidance for scholars.

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Section: Discussionmentioning

confidence: 99%

Global research trends of diabetes remission: a bibliometric study

Yang,

He,

Chen

et al. 2023

Front. Endocrinol.

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Single-Anastomosis Duodeno-ileal Bypass with Sleeve Gastrectomy as an Ultimate Option for Diabetics with Severe Obesity: A Scoping Review

Aref

2024

Curr Surg Rep

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Diabetes remission in newly diagnosed type 2 diabetes mellitus through short‐term continuous subcutaneous insulin infusion intensive therapy combined with low‐carbohydrate diet treatment

Huang,

Jiang,

Liu

et al. 2024

J of Diabetes Invest

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Aim/IntroductionTo evaluate the therapeutic efficacy short‐term continuous subcutaneous insulin infusion (CSII) intensive therapy combined with a low‐carbohydrate diet (LCD) for diabetes remission in patients with newly diagnosed type 2 diabetes mellitus.Materials and MethodsThis study included patients newly diagnosed with type 2 diabetes mellitus, who were randomly divided into two groups: conventional (conventional CSII + traditional lifestyle guidance); and intensive (intensive CSII + LCD lifestyle guidance). CSII was used for blood glucose control, with continuous glucose monitoring (CGM) used to monitor blood glucose levels. The primary outcome measure was hemoglobin A1c (HbA1c) level; secondary outcomes included body weight, body mass index (BMI), waist circumference, glycemic control, and biochemical indices.ResultsThe time in range (TIR) in the intensive treatment group was greater than that in the conventional treatment group (P < 0.05). There was no significant difference in the incidence of hypoglycemia between the two groups (P > 0.05). Compared with the conventional treatment group, diabetes remission rates were significantly greater in the intensive treatment group (P < 0.05). In the intensive treatment group, fasting plasma glucose (FPG), HbA1c, Homeostasis Model assessment of Insulin Resistance (HOMA‐IR), triglycerides (TG), low‐density lipoprotein cholesterol (LDL‐c), and changes in body weight, BMI, visceral fat area (VFA), and subcutaneous fat area (SFA) decreased significantly (P < 0.05). FPG, HOMA‐IR, TG, LDL‐c, and changes in body weight, BMI, waist circumference, and VFA were significantly correlated with HbA1c levels (P < 0.05).ConclusionsThe combination of intensive CSII and LCD lifestyle guidance had been improved the remission rate in patients with newly diagnosed type 2 diabetes mellitus.

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Outcomes of metabolic surgery in obese patients with type 2 diabetes with respect to impact on beta cell function, insulin sensitivity and diabetes remission - A study from south India

Cited by 4 publications

References 45 publications

Global research trends of diabetes remission: a bibliometric study

Global research trends of diabetes remission: a bibliometric study

Single-Anastomosis Duodeno-ileal Bypass with Sleeve Gastrectomy as an Ultimate Option for Diabetics with Severe Obesity: A Scoping Review

Diabetes remission in newly diagnosed type 2 diabetes mellitus through short‐term continuous subcutaneous insulin infusion intensive therapy combined with low‐carbohydrate diet treatment

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